ENSG00000119403


Homo sapiens

Features
Gene ID: ENSG00000119403
  
Biological name :PHF19
  
Synonyms : PHD finger protein 19 / PHF19 / Q5T6S3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q33.2
Gene start: 120855652
Gene end: 120894896
  
Corresponding Affymetrix probe sets: 225533_at (Human Genome U133 Plus 2.0 Array)   227211_at (Human Genome U133 Plus 2.0 Array)   227212_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000397935
Ensembl peptide - ENSP00000395938
Ensembl peptide - ENSP00000404655
Ensembl peptide - ENSP00000483946
Ensembl peptide - ENSP00000408479
Ensembl peptide - ENSP00000407433
Ensembl peptide - ENSP00000310372
Ensembl peptide - ENSP00000363003
NCBI entrez gene - 26147     See in Manteia.
OMIM - 609740
RefSeq - XM_017014613
RefSeq - NM_001009936
RefSeq - NM_001286840
RefSeq - NM_001286842
RefSeq - NM_001286843
RefSeq - NM_015651
RefSeq - XM_005251906
RefSeq - XM_011518509
RefSeq - XM_011518511
RefSeq - XM_011518515
RefSeq - XM_011518516
RefSeq - XM_017014612
RefSeq Peptide - NP_001273769
RefSeq Peptide - NP_001273772
RefSeq Peptide - NP_056466
RefSeq Peptide - NP_001009936
RefSeq Peptide - NP_001273771
swissprot - X6RER8
swissprot - A0A087X169
swissprot - Q5T6S3
swissprot - B0QZ72
swissprot - B0QZ51
swissprot - B0QZ50
swissprot - F5H8K3
Ensembl - ENSG00000119403
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phf19ENSDARG00000078050Danio rerio
 PHF19ENSGALG00000001595Gallus gallus
 Phf19ENSMUSG00000026873Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MTF2 / Q9Y483 / metal response element binding transcription factor 2ENSG0000014303342
PHF1 / O43189 / PHD finger protein 1ENSG0000011251138


Protein motifs (from Interpro)
Interpro ID Name
 IPR001965  Zinc finger, PHD-type
 IPR002999  Tudor domain
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR025894  Polycomb-like MTF2 factor 2, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0019827 stem cell population maintenance IEA
 biological_processGO:0045814 negative regulation of gene expression, epigenetic TAS
 biological_processGO:0048863 stem cell differentiation IEA
 biological_processGO:0061087 positive regulation of histone H3-K27 methylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0035098 ESC/E(Z) complex IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0035064 methylated histone binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
PRC2 methylates histones and DNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000106462 EZH2 / Q15910 / enhancer of zeste 2 polycomb repressive complex 2 subunit  / complex
 ENSG00000162521 RBBP4 / Q09028 / RB binding protein 4, chromatin remodeling factor  / complex
 ENSG00000074266 EED / O75530 / embryonic ectoderm development  / complex
 ENSG00000178691 SUZ12 / Q15022 / SUZ12 polycomb repressive complex 2 subunit  / complex
 ENSG00000102054 RBBP7 / Q16576 / RB binding protein 7, chromatin remodeling factor  / complex






 

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