ENSG00000120645


Homo sapiens

Features
Gene ID: ENSG00000120645
  
Biological name :IQSEC3
  
Synonyms : IQ motif and Sec7 domain 3 / IQSEC3 / Q9UPP2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p13.33
Gene start: 66765
Gene end: 178460
  
Corresponding Affymetrix probe sets: 1553949_at (Human Genome U133 Plus 2.0 Array)   1556872_s_at (Human Genome U133 Plus 2.0 Array)   213834_at (Human Genome U133 Plus 2.0 Array)   242694_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000372292
Ensembl peptide - ENSP00000437554
NCBI entrez gene - 440073     See in Manteia.
OMIM - 612118
RefSeq - XM_017019311
RefSeq - NM_001170738
RefSeq - NM_015232
RefSeq - XM_011520960
RefSeq - XM_011520961
RefSeq - XM_017019310
RefSeq - XM_011520958
RefSeq - XM_011520959
RefSeq Peptide - NP_056047
RefSeq Peptide - NP_001164209
swissprot - Q9UPP2
Ensembl - ENSG00000120645
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 iqsec3aENSDARG00000099850Danio rerio
 iqsec3bENSDARG00000093091Danio rerio
 IQSEC3ENSGALG00000012975Gallus gallus
 Iqsec3ENSMUSG00000040797Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IQSEC2 / Q5JU85 / IQ motif and Sec7 domain 2ENSG0000012431338
IQSEC1 / Q6DN90 / IQ motif and Sec7 domain 1ENSG0000014471137
Q9Y6D6 / ARFGEF1 / ADP ribosylation factor guanine nucleotide exchange factor 1ENSG0000006677718
Q9Y6D5 / ARFGEF2 / ADP ribosylation factor guanine nucleotide exchange factor 2ENSG0000012419818
CYTH2 / Q99418 / cytohesin 2ENSG0000010544310
CYTH3 / O43739 / cytohesin 3ENSG0000000825610
CYTH1 / Q15438 / cytohesin 1ENSG0000010866910
CYTH4 / Q9UIA0 / cytohesin 4ENSG000001000559
FBXO8 / Q9NRD0 / F-box protein 8ENSG000001641178
AC008403.1ENSG000002684652


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR000904  Sec7 domain
 IPR011993  PH-like domain superfamily
 IPR023394  Sec7, C-terminal domain superfamily
 IPR033742  IQ motif and SEC7 domain-containing protein, PH domain
 IPR035999  Sec7 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030036 actin cytoskeleton organization IBA
 biological_processGO:0032012 regulation of ARF protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:0060077 inhibitory synapse IEA
 molecular_functionGO:0005086 ARF guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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