ENSG00000105443


Homo sapiens

Features
Gene ID: ENSG00000105443
  
Biological name :CYTH2
  
Synonyms : CYTH2 / cytohesin 2 / Q99418
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.33
Gene start: 48469032
Gene end: 48482314
  
Corresponding Affymetrix probe sets: 1555842_at (Human Genome U133 Plus 2.0 Array)   209158_s_at (Human Genome U133 Plus 2.0 Array)   237234_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000482082
Ensembl peptide - ENSP00000486578
Ensembl peptide - ENSP00000493357
Ensembl peptide - ENSP00000493227
Ensembl peptide - ENSP00000314566
Ensembl peptide - ENSP00000375753
Ensembl peptide - ENSP00000408236
Ensembl peptide - ENSP00000472602
NCBI entrez gene - 9266     See in Manteia.
OMIM - 602488
RefSeq - XM_006723473
RefSeq - NM_004228
RefSeq - NM_017457
RefSeq - XM_006723472
RefSeq Peptide - NP_004219
RefSeq Peptide - NP_059431
swissprot - A0A286YF81
swissprot - Q8WYS2
swissprot - A0A0D9SFG6
swissprot - F8W8E2
swissprot - M0R2J0
swissprot - G5E9B7
swissprot - Q99418
Ensembl - ENSG00000105443
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYTH2ENSDARG00000028800Danio rerio
 Cyth2ENSMUSG00000003269Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYTH1 / Q15438 / cytohesin 1ENSG0000010866981
CYTH3 / O43739 / cytohesin 3ENSG0000000825680
CYTH4 / Q9UIA0 / cytohesin 4ENSG0000010005568
Q9Y6D6 / ARFGEF1 / ADP ribosylation factor guanine nucleotide exchange factor 1ENSG0000006677738
Q9Y6D5 / ARFGEF2 / ADP ribosylation factor guanine nucleotide exchange factor 2ENSG0000012419837
IQSEC1 / Q6DN90 / IQ motif and Sec7 domain 1ENSG0000014471131
IQSEC3 / Q9UPP2 / IQ motif and Sec7 domain 3ENSG0000012064530
IQSEC2 / Q5JU85 / IQ motif and Sec7 domain 2ENSG0000012431328
AC008403.1ENSG0000026846524
FBXO8 / Q9NRD0 / F-box protein 8ENSG0000016411716


Protein motifs (from Interpro)
Interpro ID Name
 IPR000904  Sec7 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR023394  Sec7, C-terminal domain superfamily
 IPR035999  Sec7 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis TAS
 biological_processGO:0030036 actin cytoskeleton organization TAS
 biological_processGO:0032012 regulation of ARF protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005086 ARF guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0070679 inositol 1,4,5 trisphosphate binding ISS


Pathways (from Reactome)
Pathway description
Intra-Golgi traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000143761 ARF1 / P84077 / ADP ribosylation factor 1  / complex / reaction






 

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