ENSG00000144711


Homo sapiens

Features
Gene ID: ENSG00000144711
  
Biological name :IQSEC1
  
Synonyms : IQ motif and Sec7 domain 1 / IQSEC1 / Q6DN90
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p25.2
Gene start: 12897220
Gene end: 13073117
  
Corresponding Affymetrix probe sets: 203906_at (Human Genome U133 Plus 2.0 Array)   203907_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000496366
Ensembl peptide - ENSP00000478001
Ensembl peptide - ENSP00000480301
Ensembl peptide - ENSP00000495163
Ensembl peptide - ENSP00000273221
NCBI entrez gene - 9922     See in Manteia.
OMIM - 610166
RefSeq - XM_017007582
RefSeq - XM_011534311
RefSeq - XM_011534312
RefSeq - XM_011534313
RefSeq - XM_011534314
RefSeq - XM_011534315
RefSeq - XM_017007581
RefSeq - NM_001134382
RefSeq - NM_014869
RefSeq - XM_011534304
RefSeq - XM_011534305
RefSeq - XM_011534306
RefSeq - XM_011534307
RefSeq - XM_011534308
RefSeq - XM_011534310
RefSeq Peptide - NP_001127854
RefSeq Peptide - NP_001317548
RefSeq Peptide - NP_055684
swissprot - A0A0C4DGT3
swissprot - Q6DN90
swissprot - A0A087WWK8
Ensembl - ENSG00000144711
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 iqsec1bENSDARG00000016551Danio rerio
 LO017700.1ENSDARG00000073822Danio rerio
 IQSEC1ENSGALG00000005042Gallus gallus
 Iqsec1ENSMUSG00000034312Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IQSEC2 / Q5JU85 / IQ motif and Sec7 domain 2ENSG0000012431358
IQSEC3 / Q9UPP2 / IQ motif and Sec7 domain 3ENSG0000012064539
Q9Y6D5 / ARFGEF2 / ADP ribosylation factor guanine nucleotide exchange factor 2ENSG0000012419819
Q9Y6D6 / ARFGEF1 / ADP ribosylation factor guanine nucleotide exchange factor 1ENSG0000006677719
CYTH3 / O43739 / cytohesin 3ENSG0000000825611
CYTH2 / Q99418 / cytohesin 2ENSG0000010544311
CYTH1 / Q15438 / cytohesin 1ENSG0000010866911
CYTH4 / Q9UIA0 / cytohesin 4ENSG0000010005510
FBXO8 / Q9NRD0 / F-box protein 8ENSG000001641178
AC008403.1ENSG000002684653


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR000904  Sec7 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR023394  Sec7, C-terminal domain superfamily
 IPR030737  IQ motif and SEC7 domain-containing protein 1
 IPR033742  IQ motif and SEC7 domain-containing protein, PH domain
 IPR035999  Sec7 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030036 actin cytoskeleton organization IBA
 biological_processGO:0032012 regulation of ARF protein signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005086 ARF guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr