ENSG00000100055


Homo sapiens

Features
Gene ID: ENSG00000100055
  
Biological name :CYTH4
  
Synonyms : CYTH4 / cytohesin 4 / Q9UIA0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.1
Gene start: 37282027
Gene end: 37315345
  
Corresponding Affymetrix probe sets: 1554335_at (Human Genome U133 Plus 2.0 Array)   211521_s_at (Human Genome U133 Plus 2.0 Array)   219183_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000248901
Ensembl peptide - ENSP00000409579
Ensembl peptide - ENSP00000405442
Ensembl peptide - ENSP00000385997
Ensembl peptide - ENSP00000384280
NCBI entrez gene - 27128     See in Manteia.
OMIM - 606514
RefSeq - XM_011530148
RefSeq - NM_001318024
RefSeq - NM_013385
RefSeq - XM_011530147
RefSeq Peptide - NP_037517
RefSeq Peptide - NP_001304953
swissprot - H0Y724
swissprot - Q9UIA0
swissprot - B1AHH4
swissprot - B1AHH5
swissprot - B1AHH6
Ensembl - ENSG00000100055
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyth4aENSDARG00000038011Danio rerio
 cyth4bENSDARG00000103984Danio rerio
 CYTH4ENSGALG00000012454Gallus gallus
 Cyth4ENSMUSG00000018008Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYTH3 / O43739 / cytohesin 3ENSG0000000825672
CYTH1 / Q15438 / cytohesin 1ENSG0000010866969
CYTH2 / Q99418 / cytohesin 2ENSG0000010544369
Q9Y6D6 / ARFGEF1 / ADP ribosylation factor guanine nucleotide exchange factor 1ENSG0000006677740
Q9Y6D5 / ARFGEF2 / ADP ribosylation factor guanine nucleotide exchange factor 2ENSG0000012419839
IQSEC1 / Q6DN90 / IQ motif and Sec7 domain 1ENSG0000014471128
IQSEC3 / Q9UPP2 / IQ motif and Sec7 domain 3ENSG0000012064527
IQSEC2 / Q5JU85 / IQ motif and Sec7 domain 2ENSG0000012431326
FBXO8 / Q9NRD0 / F-box protein 8ENSG0000016411715
AC008403.1ENSG0000026846512


Protein motifs (from Interpro)
Interpro ID Name
 IPR000904  Sec7 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR023394  Sec7, C-terminal domain superfamily
 IPR035999  Sec7 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032012 regulation of ARF protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005086 ARF guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
Intra-Golgi traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000143761 ARF1 / P84077 / ADP ribosylation factor 1  / reaction / complex






 

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