ENSG00000108669


Homo sapiens

Features
Gene ID: ENSG00000108669
  
Biological name :CYTH1
  
Synonyms : CYTH1 / cytohesin 1 / Q15438
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q25.3
Gene start: 78674048
Gene end: 78782297
  
Corresponding Affymetrix probe sets: 202879_s_at (Human Genome U133 Plus 2.0 Array)   202880_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468433
Ensembl peptide - ENSP00000466949
Ensembl peptide - ENSP00000467052
Ensembl peptide - ENSP00000354398
Ensembl peptide - ENSP00000389095
Ensembl peptide - ENSP00000465252
Ensembl peptide - ENSP00000465530
Ensembl peptide - ENSP00000465665
Ensembl peptide - ENSP00000465940
Ensembl peptide - ENSP00000465945
Ensembl peptide - ENSP00000466512
NCBI entrez gene - 9267     See in Manteia.
OMIM - 182115
RefSeq - XM_017025338
RefSeq - NM_001292018
RefSeq - NM_001292019
RefSeq - NM_004762
RefSeq - NM_017456
RefSeq - XM_011525475
RefSeq - XM_011525476
RefSeq - XM_011525477
RefSeq - XM_011525478
RefSeq - XM_017025336
RefSeq - XM_017025337
RefSeq Peptide - NP_001278948
RefSeq Peptide - NP_004753
RefSeq Peptide - NP_059430
RefSeq Peptide - NP_001278947
swissprot - K7ENQ8
swissprot - K7ERV8
swissprot - Q15438
swissprot - K7EJN5
swissprot - K7EKA2
swissprot - K7EL72
swissprot - K7ENH6
Ensembl - ENSG00000108669
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyth1aENSDARG00000076742Danio rerio
 cyth1bENSDARG00000021488Danio rerio
 CYTH1ENSGALG00000007093Gallus gallus
 Cyth1ENSMUSG00000017132Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYTH3 / O43739 / cytohesin 3ENSG0000000825684
CYTH2 / Q99418 / cytohesin 2ENSG0000010544382
CYTH4 / Q9UIA0 / cytohesin 4ENSG0000010005569
Q9Y6D6 / ARFGEF1 / ADP ribosylation factor guanine nucleotide exchange factor 1ENSG0000006677741
Q9Y6D5 / ARFGEF2 / ADP ribosylation factor guanine nucleotide exchange factor 2ENSG0000012419840
IQSEC3 / Q9UPP2 / IQ motif and Sec7 domain 3ENSG0000012064530
IQSEC1 / Q6DN90 / IQ motif and Sec7 domain 1ENSG0000014471130
IQSEC2 / Q5JU85 / IQ motif and Sec7 domain 2ENSG0000012431327
AC008403.1ENSG0000026846517
FBXO8 / Q9NRD0 / F-box protein 8ENSG0000016411715


Protein motifs (from Interpro)
Interpro ID Name
 IPR000904  Sec7 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR023394  Sec7, C-terminal domain superfamily
 IPR035999  Sec7 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016192 vesicle-mediated transport TAS
 biological_processGO:0030155 regulation of cell adhesion IDA
 biological_processGO:0032012 regulation of ARF protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0090162 establishment of epithelial cell polarity ISS
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0005923 bicellular tight junction ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane ISS
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005086 ARF guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
Intra-Golgi traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000143761 ARF1 / P84077 / ADP ribosylation factor 1  / reaction / complex






 

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