ENSG00000164117


Homo sapiens

Features
Gene ID: ENSG00000164117
  
Biological name :FBXO8
  
Synonyms : F-box protein 8 / FBXO8 / Q9NRD0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q34.1
Gene start: 174236658
Gene end: 174284264
  
Corresponding Affymetrix probe sets: 1554806_a_at (Human Genome U133 Plus 2.0 Array)   223240_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000377280
Ensembl peptide - ENSP00000484517
Ensembl peptide - ENSP00000427506
Ensembl peptide - ENSP00000427313
Ensembl peptide - ENSP00000422905
NCBI entrez gene - 26269     See in Manteia.
OMIM - 605649
RefSeq - XM_017008020
RefSeq - NM_012180
RefSeq Peptide - NP_036312
swissprot - D6RIC0
swissprot - D6RJ92
swissprot - Q9NRD0
swissprot - A0A0S2Z5D1
Ensembl - ENSG00000164117
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxo8ENSDARG00000007477Danio rerio
 FBXO8ENSGALG00000010764Gallus gallus
 Fbxo8ENSMUSG00000038206Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IQSEC2 / Q5JU85 / IQ motif and Sec7 domain 2ENSG0000012431328
IQSEC3 / Q9UPP2 / IQ motif and Sec7 domain 3ENSG0000012064528
IQSEC1 / Q6DN90 / IQ motif and Sec7 domain 1ENSG0000014471127
Q9Y6D6 / ARFGEF1 / ADP ribosylation factor guanine nucleotide exchange factor 1ENSG0000006677726
Q9Y6D5 / ARFGEF2 / ADP ribosylation factor guanine nucleotide exchange factor 2ENSG0000012419825
CYTH2 / Q99418 / cytohesin 2ENSG0000010544319
CYTH3 / O43739 / cytohesin 3ENSG0000000825619
CYTH4 / Q9UIA0 / cytohesin 4ENSG0000010005519
CYTH1 / Q15438 / cytohesin 1ENSG0000010866918
AC008403.1ENSG000002684655


Protein motifs (from Interpro)
Interpro ID Name
 IPR000904  Sec7 domain
 IPR001810  F-box domain
 IPR023394  Sec7, C-terminal domain superfamily
 IPR035999  Sec7 domain superfamily
 IPR036047  F-box-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process NAS
 biological_processGO:0032012 regulation of ARF protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0000151 ubiquitin ligase complex NAS
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005086 ARF guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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