ENSG00000125522


Homo sapiens

Features
Gene ID: ENSG00000125522
  
Biological name :NPBWR2
  
Synonyms : neuropeptides B and W receptor 2 / NPBWR2 / P48146
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q13.33
Gene start: 64105820
Gene end: 64107171
  
Corresponding Affymetrix probe sets: 221358_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358783
NCBI entrez gene - 2832     See in Manteia.
OMIM - 600731
RefSeq - NM_005286
RefSeq Peptide - NP_005277
swissprot - P48146
Ensembl - ENSG00000125522
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 npbwr2aENSDARG00000079423Danio rerio
 NPBWR2ENSGALG00000029170Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NPBWR1 / P48145 / neuropeptides B and W receptor 1ENSG0000018372960
SSTR5 / P35346 / somatostatin receptor 5ENSG0000016200941
SSTR3 / P32745 / somatostatin receptor 3ENSG0000027819538
OPRD1 / P41143 / opioid receptor delta 1ENSG0000011632937
OPRK1 / P41145 / opioid receptor kappa 1ENSG0000008255637
SSTR2 / P30874 / somatostatin receptor 2ENSG0000018061637
SSTR4 / P31391 / somatostatin receptor 4ENSG0000013267137
OPRM1 / P35372 / opioid receptor mu 1ENSG0000011203836
SSTR1 / P30872 / somatostatin receptor 1ENSG0000013987436
OPRL1 / P41146 / opioid related nociceptin receptor 1ENSG0000012551034
MCHR2 / Q969V1 / melanin concentrating hormone receptor 2ENSG0000015203427
MCHR1 / Q99705 / melanin concentrating hormone receptor 1ENSG0000012828526


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR009150  Neuropeptide B/W receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR027349  Neuropeptide B/W receptor 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IDA
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IBA
 biological_processGO:0007218 neuropeptide signaling pathway IBA
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0038003 opioid receptor signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IC
 cellular_componentGO:0043005 neuron projection IBA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004985 opioid receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008188 neuropeptide receptor activity IEA
 molecular_functionGO:0042923 neuropeptide binding IBA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000183971 NPW / Q8N729 / neuropeptide W  / complex / reaction
 ENSG00000183979 NPB / Q8NG41 / neuropeptide B  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr