ENSG00000116329


Homo sapiens

Features
Gene ID: ENSG00000116329
  
Biological name :OPRD1
  
Synonyms : opioid receptor delta 1 / OPRD1 / P41143
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p35.3
Gene start: 28812142
Gene end: 28871267
  
Corresponding Affymetrix probe sets: 1559110_at (Human Genome U133 Plus 2.0 Array)   1559111_a_at (Human Genome U133 Plus 2.0 Array)   207792_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000234961
Ensembl peptide - ENSP00000477970
NCBI entrez gene - 4985     See in Manteia.
OMIM - 165195
RefSeq - NM_000911
RefSeq Peptide - NP_000902
swissprot - D2CGC9
swissprot - P41143
Ensembl - ENSG00000116329
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 oprd1aENSDARG00000041660Danio rerio
 oprd1bENSDARG00000037159Danio rerio
 ENSGALG00000036782Gallus gallus
 Oprd1ENSMUSG00000050511Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OPRM1 / P35372 / opioid receptor mu 1ENSG0000011203861
OPRK1 / P41145 / opioid receptor kappa 1ENSG0000008255657
OPRL1 / P41146 / opioid related nociceptin receptor 1ENSG0000012551051
SSTR4 / P31391 / somatostatin receptor 4ENSG0000013267137
SSTR1 / P30872 / somatostatin receptor 1ENSG0000013987436
SSTR2 / P30874 / somatostatin receptor 2ENSG0000018061635
SSTR5 / P35346 / somatostatin receptor 5ENSG0000016200934
SSTR3 / P32745 / somatostatin receptor 3ENSG0000027819534
NPBWR2 / P48146 / neuropeptides B and W receptor 2ENSG0000012552233
NPBWR1 / P48145 / neuropeptides B and W receptor 1ENSG0000018372931
MCHR1 / Q99705 / melanin concentrating hormone receptor 1ENSG0000012828526
MCHR2 / Q969V1 / melanin concentrating hormone receptor 2ENSG0000015203426


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000321  Delta opioid receptor
 IPR001418  Opioid receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000060 protein import into nucleus, translocation IDA
 biological_processGO:0006955 immune response TAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS
 biological_processGO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0008344 adult locomotory behavior IEA
 biological_processGO:0010629 negative regulation of gene expression IDA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0019233 sensory perception of pain IBA
 biological_processGO:0032460 negative regulation of protein oligomerization IDA
 biological_processGO:0032793 positive regulation of CREB transcription factor activity IC
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IDA
 biological_processGO:0038003 opioid receptor signaling pathway IEA
 biological_processGO:0042755 eating behavior IEA
 biological_processGO:0051881 regulation of mitochondrial membrane potential IDA
 biological_processGO:0051924 regulation of calcium ion transport IEA
 biological_processGO:0051930 regulation of sensory perception of pain IEA
 biological_processGO:0071363 cellular response to growth factor stimulus IEA
 biological_processGO:0071456 cellular response to hypoxia IDA
 biological_processGO:0097237 cellular response to toxic substance IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031226 intrinsic component of plasma membrane IDA
 cellular_componentGO:0031982 vesicle IEA
 cellular_componentGO:0032590 dendrite membrane IEA
 cellular_componentGO:0043005 neuron projection IBA
 cellular_componentGO:0043679 axon terminus IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004985 opioid receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0038046 enkephalin receptor activity IEA
 molecular_functionGO:0042923 neuropeptide binding IBA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events
Interleukin-4 and Interleukin-13 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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