ENSG00000278195


Homo sapiens

Features
Gene ID: ENSG00000278195
  
Biological name :SSTR3
  
Synonyms : P32745 / somatostatin receptor 3 / SSTR3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q13.1
Gene start: 37204238
Gene end: 37212322
  
Corresponding Affymetrix probe sets: 1553178_a_at (Human Genome U133 Plus 2.0 Array)   214491_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000480971
Ensembl peptide - ENSP00000481325
NCBI entrez gene - 6753     See in Manteia.
OMIM - 182453
RefSeq - XM_017028924
RefSeq - NM_001051
RefSeq - NM_001278687
RefSeq - XM_006724311
RefSeq - XM_011530349
RefSeq - XM_017028923
RefSeq - XM_005261721
RefSeq Peptide - NP_001265616
RefSeq Peptide - NP_001042
swissprot - P32745
Ensembl - ENSG00000278195
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:zfos-169g10.2ENSDARG00000103662Danio rerio
 sstr3ENSDARG00000014477Danio rerio
 SSTR3ENSGALG00000012457Gallus gallus
 Sstr3ENSMUSG00000044933Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SSTR5 / P35346 / somatostatin receptor 5ENSG0000016200948
SSTR2 / P30874 / somatostatin receptor 2ENSG0000018061641
SSTR4 / P31391 / somatostatin receptor 4ENSG0000013267140
SSTR1 / P30872 / somatostatin receptor 1ENSG0000013987440
OPRL1 / P41146 / opioid related nociceptin receptor 1ENSG0000012551033
NPBWR1 / P48145 / neuropeptides B and W receptor 1ENSG0000018372932
OPRK1 / P41145 / opioid receptor kappa 1ENSG0000008255631
NPBWR2 / P48146 / neuropeptides B and W receptor 2ENSG0000012552231
OPRD1 / P41143 / opioid receptor delta 1ENSG0000011632930
OPRM1 / P35372 / opioid receptor mu 1ENSG0000011203829
MCHR1 / Q99705 / melanin concentrating hormone receptor 1ENSG0000012828527
MCHR2 / Q969V1 / melanin concentrating hormone receptor 2ENSG0000015203425


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000586  Somatostatin receptor family
 IPR001856  Somatostatin receptor 3
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS
 biological_processGO:0007218 neuropeptide signaling pathway IBA
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0008628 hormone-mediated apoptotic signaling pathway TAS
 biological_processGO:0021549 cerebellum development IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0038170 somatostatin signaling pathway IEA
 biological_processGO:0042594 response to starvation IEA
 biological_processGO:0071385 cellular response to glucocorticoid stimulus IEA
 biological_processGO:0071392 cellular response to estradiol stimulus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043005 neuron projection IBA
 cellular_componentGO:0060170 ciliary membrane TAS
 cellular_componentGO:0097730 non-motile cilium ISS
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IBA
 molecular_functionGO:0004994 somatostatin receptor activity TAS
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042923 neuropeptide binding IBA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events
BBSome-mediated cargo-targeting to cilium


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000113966 ARL6 / Q9H0F7 / ADP ribosylation factor like GTPase 6  / reaction / complex






 

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