ENSG00000162009


Homo sapiens

Features
Gene ID: ENSG00000162009
  
Biological name :SSTR5
  
Synonyms : P35346 / somatostatin receptor 5 / SSTR5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p13.3
Gene start: 1078781
Gene end: 1080142
  
Corresponding Affymetrix probe sets: 214555_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000293897
NCBI entrez gene - 6755     See in Manteia.
OMIM - 182455
RefSeq - NM_001172560
RefSeq - NM_001053
RefSeq Peptide - NP_001044
RefSeq Peptide - NP_001166031
swissprot - P35346
Ensembl - ENSG00000162009
  
Related genetic diseases (OMIM): 182455 - Somatostatin analog, resistance to
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sstr5ENSDARG00000101655Danio rerio
 SSTR5ENSGALG00000005258Gallus gallus
 Sstr5ENSMUSG00000050824Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SSTR3 / P32745 / somatostatin receptor 3ENSG0000027819555
SSTR2 / P30874 / somatostatin receptor 2ENSG0000018061650
SSTR4 / P31391 / somatostatin receptor 4ENSG0000013267148
SSTR1 / P30872 / somatostatin receptor 1ENSG0000013987445
NPBWR2 / P48146 / neuropeptides B and W receptor 2ENSG0000012552237
OPRL1 / P41146 / opioid related nociceptin receptor 1ENSG0000012551036
OPRD1 / P41143 / opioid receptor delta 1ENSG0000011632935
OPRM1 / P35372 / opioid receptor mu 1ENSG0000011203834
NPBWR1 / P48145 / neuropeptides B and W receptor 1ENSG0000018372934
OPRK1 / P41145 / opioid receptor kappa 1ENSG0000008255632
MCHR1 / Q99705 / melanin concentrating hormone receptor 1ENSG0000012828529
MCHR2 / Q969V1 / melanin concentrating hormone receptor 2ENSG0000015203429


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000586  Somatostatin receptor family
 IPR001184  Somatostatin receptor 5
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0032467 positive regulation of cytokinesis IMP
 biological_processGO:0038170 somatostatin signaling pathway IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0050796 regulation of insulin secretion IEA
 biological_processGO:0071385 cellular response to glucocorticoid stimulus IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043005 neuron projection IBA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004994 somatostatin receptor activity IBA
 molecular_functionGO:0042923 neuropeptide binding IBA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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