ENSG00000139874


Homo sapiens

Features
Gene ID: ENSG00000139874
  
Biological name :SSTR1
  
Synonyms : P30872 / somatostatin receptor 1 / SSTR1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q21.1
Gene start: 38207999
Gene end: 38213067
  
Corresponding Affymetrix probe sets: 208482_at (Human Genome U133 Plus 2.0 Array)   235591_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000267377
NCBI entrez gene - 6751     See in Manteia.
OMIM - 182451
RefSeq - NM_001049
RefSeq Peptide - NP_001040
swissprot - P30872
Ensembl - ENSG00000139874
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sstr1aENSDARG00000104922Danio rerio
 SSTR1ENSGALG00000010139Gallus gallus
 Sstr1ENSMUSG00000035431Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SSTR4 / P31391 / somatostatin receptor 4ENSG0000013267158
SSTR3 / P32745 / somatostatin receptor 3ENSG0000027819543
SSTR2 / P30874 / somatostatin receptor 2ENSG0000018061642
SSTR5 / P35346 / somatostatin receptor 5ENSG0000016200941
OPRD1 / P41143 / opioid receptor delta 1ENSG0000011632935
OPRM1 / P35372 / opioid receptor mu 1ENSG0000011203834
OPRK1 / P41145 / opioid receptor kappa 1ENSG0000008255633
OPRL1 / P41146 / opioid related nociceptin receptor 1ENSG0000012551031
NPBWR2 / P48146 / neuropeptides B and W receptor 2ENSG0000012552230
NPBWR1 / P48145 / neuropeptides B and W receptor 1ENSG0000018372928
MCHR1 / Q99705 / melanin concentrating hormone receptor 1ENSG0000012828526
MCHR2 / Q969V1 / melanin concentrating hormone receptor 2ENSG0000015203424


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000586  Somatostatin receptor family
 IPR001116  Somatostatin receptor 1
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS
 biological_processGO:0007215 glutamate receptor signaling pathway IEA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0021549 cerebellum development IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0038170 somatostatin signaling pathway IEA
 biological_processGO:0042594 response to starvation IEA
 biological_processGO:0071392 cellular response to estradiol stimulus IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043005 neuron projection IBA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004994 somatostatin receptor activity TAS
 molecular_functionGO:0042923 neuropeptide binding IBA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr