ENSG00000180616


Homo sapiens

Features
Gene ID: ENSG00000180616
  
Biological name :SSTR2
  
Synonyms : P30874 / somatostatin receptor 2 / SSTR2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q25.1
Gene start: 73165012
Gene end: 73176633
  
Corresponding Affymetrix probe sets: 214597_at (Human Genome U133 Plus 2.0 Array)   217455_s_at (Human Genome U133 Plus 2.0 Array)   233310_at (Human Genome U133 Plus 2.0 Array)   239031_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000350198
NCBI entrez gene - 6752     See in Manteia.
OMIM - 182452
RefSeq - NM_001050
RefSeq Peptide - NP_001041
swissprot - P30874
Ensembl - ENSG00000180616
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sstr2aENSDARG00000059090Danio rerio
 sstr2bENSDARG00000069806Danio rerio
 SSTR2ENSGALG00000004418Gallus gallus
 Sstr2ENSMUSG00000047904Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SSTR5 / P35346 / somatostatin receptor 5ENSG0000016200950
SSTR3 / P32745 / somatostatin receptor 3ENSG0000027819547
SSTR1 / P30872 / somatostatin receptor 1ENSG0000013987445
SSTR4 / P31391 / somatostatin receptor 4ENSG0000013267144
OPRM1 / P35372 / opioid receptor mu 1ENSG0000011203836
OPRD1 / P41143 / opioid receptor delta 1ENSG0000011632935
OPRK1 / P41145 / opioid receptor kappa 1ENSG0000008255634
OPRL1 / P41146 / opioid related nociceptin receptor 1ENSG0000012551033
NPBWR2 / P48146 / neuropeptides B and W receptor 2ENSG0000012552233
NPBWR1 / P48145 / neuropeptides B and W receptor 1ENSG0000018372930
MCHR1 / Q99705 / melanin concentrating hormone receptor 1ENSG0000012828529
MCHR2 / Q969V1 / melanin concentrating hormone receptor 2ENSG0000015203426


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000586  Somatostatin receptor family
 IPR002074  Somatostatin receptor 2
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006937 regulation of muscle contraction IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS
 biological_processGO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0021549 cerebellum development IEA
 biological_processGO:0030432 peristalsis IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0038170 somatostatin signaling pathway IEA
 biological_processGO:0042594 response to starvation IEA
 biological_processGO:0071385 cellular response to glucocorticoid stimulus IEA
 biological_processGO:0071392 cellular response to estradiol stimulus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043005 neuron projection IBA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004994 somatostatin receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030165 PDZ domain binding IEA
 molecular_functionGO:0042923 neuropeptide binding IBA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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