ENSG00000128285


Homo sapiens

Features
Gene ID: ENSG00000128285
  
Biological name :MCHR1
  
Synonyms : MCHR1 / melanin concentrating hormone receptor 1 / Q99705
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.2
Gene start: 40678750
Gene end: 40682814
  
Corresponding Affymetrix probe sets: 221354_s_at (Human Genome U133 Plus 2.0 Array)   223855_s_at (Human Genome U133 Plus 2.0 Array)   230498_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000249016
Ensembl peptide - ENSP00000370841
NCBI entrez gene - 2847     See in Manteia.
OMIM - 601751
RefSeq - NM_005297
RefSeq Peptide - NP_005288
swissprot - A6ZJ87
swissprot - Q99705
Ensembl - ENSG00000128285
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mchr1aENSDARG00000104093Danio rerio
 mchr1bENSDARG00000022525Danio rerio
 MCHR1ENSGALG00000019736Gallus gallus
 Mchr1ENSMUSG00000050164Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SSTR3 / P32745 / somatostatin receptor 3ENSG0000027819527
MCHR2 / Q969V1 / melanin concentrating hormone receptor 2ENSG0000015203427
SSTR5 / P35346 / somatostatin receptor 5ENSG0000016200925
SSTR2 / P30874 / somatostatin receptor 2ENSG0000018061625
SSTR4 / P31391 / somatostatin receptor 4ENSG0000013267124
SSTR1 / P30872 / somatostatin receptor 1ENSG0000013987424
NPBWR1 / P48145 / neuropeptides B and W receptor 1ENSG0000018372924
OPRD1 / P41143 / opioid receptor delta 1ENSG0000011632923
OPRM1 / P35372 / opioid receptor mu 1ENSG0000011203823
OPRL1 / P41146 / opioid related nociceptin receptor 1ENSG0000012551023
OPRK1 / P41145 / opioid receptor kappa 1ENSG0000008255621
NPBWR2 / P48146 / neuropeptides B and W receptor 2ENSG0000012552221


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR004047  Melanin-concentrating hormone 1 receptor
 IPR008361  Melanin-concentrating hormone receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006091 generation of precursor metabolites and energy TAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0007631 feeding behavior TAS
 biological_processGO:0051928 positive regulation of calcium ion transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0060170 ciliary membrane IEA
 cellular_componentGO:0097730 non-motile cilium IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0008188 neuropeptide receptor activity TAS
 molecular_functionGO:0030273 melanin-concentrating hormone receptor activity IEA
 molecular_functionGO:0042562 hormone binding IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events
BBSome-mediated cargo-targeting to cilium


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000183395 PMCH / P20382 / pro-melanin concentrating hormone  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr