ENSG00000125817


Homo sapiens

Features
Gene ID: ENSG00000125817
  
Biological name :CENPB
  
Synonyms : CENPB / centromere protein B / P07199
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: p13
Gene start: 3783851
Gene end: 3786690
  
Corresponding Affymetrix probe sets: 212437_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000369075
NCBI entrez gene - 1059     See in Manteia.
OMIM - 117140
RefSeq - NM_001810
RefSeq Peptide - NP_001801
swissprot - P07199
Ensembl - ENSG00000125817
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CenpbENSMUSG00000068267Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TIGD4 / Q8IY51 / tigger transposable element derived 4ENSG0000016998924
TIGD6 / Q17RP2 / tigger transposable element derived 6ENSG0000016429623
TIGD3 / Q6B0B8 / tigger transposable element derived 3ENSG0000017382520
JRKL / Q9Y4A0 / JRK likeENSG0000018334019
JRK / Jrk helix-turn-helix proteinENSG0000023461619
TIGD5 / Q53EQ6 / tigger transposable element derived 5ENSG0000017988618
TIGD2 / Q4W5G0 / tigger transposable element derived 2ENSG0000018034618
TIGD7 / Q6NT04 / tigger transposable element derived 7ENSG0000014099318
TIGD1 / Q96MW7 / tigger transposable element derived 1ENSG0000022194417


Protein motifs (from Interpro)
Interpro ID Name
 IPR004875  DDE superfamily endonuclease domain
 IPR006600  HTH CenpB-type DNA-binding domain
 IPR007889  DNA binding HTH domain, Psq-type
 IPR009057  Homeobox-like domain superfamily
 IPR015115  Centromere protein CENP-B, C-terminal domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR033062  Major centromere autoantigen B
 IPR034882  CENP-B, dimerisation domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0000775 chromosome, centromeric region IDA
 cellular_componentGO:0000780 condensed nuclear chromosome, centromeric region IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0031618 nuclear pericentric heterochromatin IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding NAS
 molecular_functionGO:0003696 satellite DNA binding NAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019237 centromeric DNA binding IC
 molecular_functionGO:0043565 sequence-specific DNA binding TAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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