ENSG00000129749


Homo sapiens

Features
Gene ID: ENSG00000129749
  
Biological name :CHRNA10
  
Synonyms : cholinergic receptor nicotinic alpha 10 subunit / CHRNA10 / Q9GZZ6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p15.4
Gene start: 3665587
Gene end: 3671384
  
Corresponding Affymetrix probe sets: 1568675_at (Human Genome U133 Plus 2.0 Array)   220210_at (Human Genome U133 Plus 2.0 Array)   239717_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000432757
Ensembl peptide - ENSP00000437107
Ensembl peptide - ENSP00000250699
NCBI entrez gene - 57053     See in Manteia.
OMIM - 606372
RefSeq - XM_011520234
RefSeq - NM_001303034
RefSeq - NM_001303035
RefSeq - NM_020402
RefSeq Peptide - NP_001289963
RefSeq Peptide - NP_001289964
RefSeq Peptide - NP_065135
swissprot - E9PNT7
swissprot - E9PNX2
swissprot - Q9GZZ6
Ensembl - ENSG00000129749
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Chrna10ENSMUSG00000066279Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CHRNA9 / Q9UGM1 / cholinergic receptor nicotinic alpha 9 subunitENSG0000017434355
CHRNA7 / P36544 / cholinergic receptor nicotinic alpha 7 subunitENSG0000017534440
CHRNB1 / P11230 / cholinergic receptor nicotinic beta 1 subunitENSG0000017017532
CHRNE / Q04844 / cholinergic receptor nicotinic epsilon subunitENSG0000010855631
Q494W8 / CHRFAM7A / CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusionENSG0000016666431
CHRND / Q07001 / cholinergic receptor nicotinic delta subunitENSG0000013590231
CHRNG / P07510 / cholinergic receptor nicotinic gamma subunitENSG0000019681131
HTR3A / P46098 / 5-hydroxytryptamine receptor 3AENSG0000016673628
HTR3E / A5X5Y0 / 5-hydroxytryptamine receptor 3EENSG0000018603822
HTR3C / Q8WXA8 / 5-hydroxytryptamine receptor 3CENSG0000017808422
HTR3B / O95264 / 5-hydroxytryptamine receptor 3BENSG0000014930520
HTR3D / Q70Z44 / 5-hydroxytryptamine receptor 3DENSG0000018609018


Protein motifs (from Interpro)
Interpro ID Name
 IPR002394  Nicotinic acetylcholine receptor
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR018000  Neurotransmitter-gated ion-channel, conserved site
 IPR036719  Neurotransmitter-gated ion-channel transmembrane domain superfamily
 IPR036734  Neurotransmitter-gated ion-channel ligand-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IGI
 biological_processGO:0007271 synaptic transmission, cholinergic IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0042127 regulation of cell proliferation TAS
 biological_processGO:0042472 inner ear morphogenesis IEA
 biological_processGO:0050910 detection of mechanical stimulus involved in sensory perception of sound IEA
 biological_processGO:0060078 regulation of postsynaptic membrane potential IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005892 acetylcholine-gated channel complex IEA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0043204 perikaryon IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005102 signaling receptor binding TAS
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0005262 calcium channel activity IEA
 molecular_functionGO:0022848 acetylcholine-gated cation-selective channel activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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