ENSG00000174343


Homo sapiens

Features
Gene ID: ENSG00000174343
  
Biological name :CHRNA9
  
Synonyms : cholinergic receptor nicotinic alpha 9 subunit / CHRNA9 / Q9UGM1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: p14
Gene start: 40335329
Gene end: 40355217
  
Corresponding Affymetrix probe sets: 221107_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000312663
NCBI entrez gene - 55584     See in Manteia.
OMIM - 605116
RefSeq - NM_017581
RefSeq Peptide - NP_060051
swissprot - Q9UGM1
Ensembl - ENSG00000174343
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chrna9ENSDARG00000054680Danio rerio
 LO018568.1ENSDARG00000099181Danio rerio
 CHRNA9ENSGALG00000014268Gallus gallus
 Chrna9ENSMUSG00000029205Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9GZZ6 / CHRNA10 / cholinergic receptor nicotinic alpha 10 subunitENSG0000012974952
CHRNA7 / P36544 / cholinergic receptor nicotinic alpha 7 subunitENSG0000017534435
CHRNG / P07510 / cholinergic receptor nicotinic gamma subunitENSG0000019681129
Q494W8 / CHRFAM7A / CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusionENSG0000016666429
CHRND / Q07001 / cholinergic receptor nicotinic delta subunitENSG0000013590228
CHRNB1 / P11230 / cholinergic receptor nicotinic beta 1 subunitENSG0000017017528
CHRNE / Q04844 / cholinergic receptor nicotinic epsilon subunitENSG0000010855627
HTR3A / P46098 / 5-hydroxytryptamine receptor 3AENSG0000016673624
HTR3C / Q8WXA8 / 5-hydroxytryptamine receptor 3CENSG0000017808421
HTR3B / O95264 / 5-hydroxytryptamine receptor 3BENSG0000014930520
HTR3E / A5X5Y0 / 5-hydroxytryptamine receptor 3EENSG0000018603819
HTR3D / Q70Z44 / 5-hydroxytryptamine receptor 3DENSG0000018609016


Protein motifs (from Interpro)
Interpro ID Name
 IPR002394  Nicotinic acetylcholine receptor
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR018000  Neurotransmitter-gated ion-channel, conserved site
 IPR036719  Neurotransmitter-gated ion-channel transmembrane domain superfamily
 IPR036734  Neurotransmitter-gated ion-channel ligand-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IGI
 biological_processGO:0007605 sensory perception of sound IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0042472 inner ear morphogenesis IEA
 biological_processGO:0050910 detection of mechanical stimulus involved in sensory perception of sound IEA
 biological_processGO:0060078 regulation of postsynaptic membrane potential IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0005892 acetylcholine-gated channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0005262 calcium channel activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015276 ligand-gated ion channel activity TAS
 molecular_functionGO:0022848 acetylcholine-gated cation-selective channel activity IDA


Pathways (from Reactome)
Pathway description
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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