ENSG00000186090


Homo sapiens

Features
Gene ID: ENSG00000186090
  
Biological name :HTR3D
  
Synonyms : 5-hydroxytryptamine receptor 3D / HTR3D / Q70Z44
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q27.1
Gene start: 184031544
Gene end: 184039369
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000334315
Ensembl peptide - ENSP00000371929
Ensembl peptide - ENSP00000389268
Ensembl peptide - ENSP00000405409
NCBI entrez gene - 200909     See in Manteia.
OMIM - 610122
RefSeq - XM_017005854
RefSeq - NM_001145143
RefSeq - NM_001163646
RefSeq - NM_182537
RefSeq Peptide - NP_001138615
RefSeq Peptide - NP_001157118
RefSeq Peptide - NP_872343
swissprot - Q70Z44
swissprot - F6WC43
Ensembl - ENSG00000186090
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HTR3CENSDARG00000077959Danio rerio
 ENSGALG00000026015Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HTR3E / A5X5Y0 / 5-hydroxytryptamine receptor 3EENSG0000018603861
HTR3C / Q8WXA8 / 5-hydroxytryptamine receptor 3CENSG0000017808457
HTR3A / P46098 / 5-hydroxytryptamine receptor 3AENSG0000016673627
HTR3B / O95264 / 5-hydroxytryptamine receptor 3BENSG0000014930519
CHRNA7 / P36544 / cholinergic receptor nicotinic alpha 7 subunitENSG0000017534419
Q9GZZ6 / CHRNA10 / cholinergic receptor nicotinic alpha 10 subunitENSG0000012974918
CHRNA9 / Q9UGM1 / cholinergic receptor nicotinic alpha 9 subunitENSG0000017434317
CHRND / Q07001 / cholinergic receptor nicotinic delta subunitENSG0000013590217
CHRNB1 / P11230 / cholinergic receptor nicotinic beta 1 subunitENSG0000017017516
CHRNG / P07510 / cholinergic receptor nicotinic gamma subunitENSG0000019681115
Q494W8 / CHRFAM7A / CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusionENSG0000016666415
CHRNE / Q04844 / cholinergic receptor nicotinic epsilon subunitENSG0000010855615


Protein motifs (from Interpro)
Interpro ID Name
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR036719  Neurotransmitter-gated ion-channel transmembrane domain superfamily
 IPR036734  Neurotransmitter-gated ion-channel ligand-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007268 chemical synaptic transmission TAS
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0022850 serotonin-gated cation-selective channel activity IDA


Pathways (from Reactome)
Pathway description
Neurotransmitter receptors and postsynaptic signal transmission


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000166736 HTR3A / P46098 / 5-hydroxytryptamine receptor 3A  / complex
 ENSG00000186090 HTR3D / Q70Z44 / 5-hydroxytryptamine receptor 3D  / complex






 

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