ENSG00000136014


Homo sapiens

Features
Gene ID: ENSG00000136014
  
Biological name :USP44
  
Synonyms : Q9H0E7 / ubiquitin specific peptidase 44 / USP44
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q22
Gene start: 95516560
Gene end: 95551490
  
Corresponding Affymetrix probe sets: 224048_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000448670
Ensembl peptide - ENSP00000448601
Ensembl peptide - ENSP00000449635
Ensembl peptide - ENSP00000258499
Ensembl peptide - ENSP00000376806
Ensembl peptide - ENSP00000442629
NCBI entrez gene - 84101     See in Manteia.
OMIM - 610993
RefSeq - XM_017020011
RefSeq - XM_005269173
RefSeq - XM_005269174
RefSeq - XM_011538800
RefSeq - XM_011538801
RefSeq - XM_011538802
RefSeq - XM_011538803
RefSeq - XM_011538804
RefSeq - XM_011538805
RefSeq - XM_017020009
RefSeq - XM_017020010
RefSeq - NM_001042403
RefSeq - NM_001278393
RefSeq - NM_001347936
RefSeq - NM_001347937
RefSeq - NM_032147
RefSeq - XM_005269172
RefSeq Peptide - NP_001265322
RefSeq Peptide - NP_001334865
RefSeq Peptide - NP_001334866
RefSeq Peptide - NP_115523
RefSeq Peptide - NP_001035862
swissprot - F8VRI7
swissprot - F8VRW0
swissprot - F8VVD6
swissprot - Q9H0E7
swissprot - A0A024RBD7
Ensembl - ENSG00000136014
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usp44ENSDARG00000089861Danio rerio
 USP44ENSGALG00000011400Gallus gallus
 Usp44ENSMUSG00000020020Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
USP49 / Q70CQ1 / ubiquitin specific peptidase 49ENSG0000016466359
USP3 / Q9Y6I4 / ubiquitin specific peptidase 3ENSG0000014045525
USP22 / Q9UPT9 / ubiquitin specific peptidase 22ENSG0000012442221
USP51 / Q70EK9 / ubiquitin specific peptidase 51ENSG0000024774621
A6NNY8 / USP27X / ubiquitin specific peptidase 27, X-linkedENSG0000027382019
USP42 / Q9H9J4 / ubiquitin specific peptidase 42ENSG0000010634617
USP36 / Q9P275 / ubiquitin specific peptidase 36ENSG0000005548317
C9JJH3 / USP17L10 / ubiquitin specific peptidase 17-like family member 10ENSG0000023139615
Q6R6M4 / USP17L2 / ubiquitin specific peptidase 17-like family member 2ENSG0000022344315
C9JPN9 / USP17L12 / ubiquitin specific peptidase 17-like family member 12ENSG0000022755114
A6NCW7 / USP17L4 / ubiquitin specific peptidase 17-like family member 4ENSG0000023612514
A6NCW0 / USP17L3 / ubiquitin specific peptidase 17-like family member 3ENSG0000022532714
C9J2P7 / USP17L15 / ubiquitin specific peptidase 17-like family member 15ENSG0000022356914
Q7RTZ2 / USP17L1 / ubiquitin specific peptidase 17-like family member 1ENSG0000023054914
Q0WX57 / USP17L25 / ubiquitin specific peptidase 17-like family member 25ENSG0000023043014
Q0WX57 / USP17L27 / ubiquitin specific peptidase 17-like family member 27ENSG0000023578014
D6RJB6 / USP17L20 / ubiquitin specific peptidase 17-like family member 20ENSG0000025074514
D6R9N7 / USP17L18 / ubiquitin specific peptidase 17-like family member 18ENSG0000025084414
Q0WX57 / USP17L24 / ubiquitin specific peptidase 17-like family member 24ENSG0000023226414
P0C7H9 / USP17L7 / ubiquitin specific peptidase 17-like family member 7ENSG0000022643014


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR001607  Zinc finger, UBP-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016579 protein deubiquitination IDA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process ISS
 biological_processGO:0051301 cell division IEA
 biological_processGO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint ISS
 biological_processGO:1904667 negative regulation of ubiquitin protein ligase activity IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity TAS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000117399 CDC20 / Q12834 / cell division cycle 20  / complex






 

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