ENSG00000139178


Homo sapiens

Features
Gene ID: ENSG00000139178
  
Biological name :C1RL
  
Synonyms : C1RL / complement C1r subcomponent like / Q9NZP8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p13.31
Gene start: 7089587
Gene end: 7109273
  
Corresponding Affymetrix probe sets: 218983_at (Human Genome U133 Plus 2.0 Array)   233645_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000444157
Ensembl peptide - ENSP00000441885
Ensembl peptide - ENSP00000442611
Ensembl peptide - ENSP00000266542
Ensembl peptide - ENSP00000437398
Ensembl peptide - ENSP00000437569
Ensembl peptide - ENSP00000438286
Ensembl peptide - ENSP00000438951
Ensembl peptide - ENSP00000439180
NCBI entrez gene - 51279     See in Manteia.
OMIM - 608974
RefSeq - XM_017019404
RefSeq - NM_001297640
RefSeq - NM_001297642
RefSeq - NM_001297643
RefSeq - NM_016546
RefSeq - XM_017019397
RefSeq - XM_017019398
RefSeq - XM_017019399
RefSeq - XM_017019400
RefSeq - XM_017019401
RefSeq - XM_017019402
RefSeq - XM_017019403
RefSeq Peptide - NP_001284572
RefSeq Peptide - NP_057630
RefSeq Peptide - NP_001284571
RefSeq Peptide - NP_001284569
swissprot - H0YF87
swissprot - H0YFJ9
swissprot - H0YFL7
swissprot - H0YGP8
swissprot - Q9NZP8
swissprot - F5GWF3
swissprot - F5H2Z5
swissprot - F5H6S5
swissprot - F5H7C8
Ensembl - ENSG00000139178
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000014659Gallus gallus
 C1rlENSMUSG00000038527Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
C1R / P00736 / complement C1rENSG0000015940351
MASP1 / P48740 / mannan binding lectin serine peptidase 1ENSG0000012724131
C1S / P09871 / complement C1sENSG0000018232630
MASP2 / O00187 / mannan binding lectin serine peptidase 2ENSG0000000972429
F9 / P00740 / coagulation factor IXENSG0000010198121
PAMR1 / Q6UXH9 / peptidase domain containing associated with muscle regeneration 1ENSG0000014909021
F10 / P00742 / coagulation factor XENSG0000012621821
PROC / P04070 / protein C, inactivator of coagulation factors Va and VIIIaENSG0000011571819
HP / P00738 / haptoglobinENSG0000025701718
HPR / P00739 / haptoglobin-related proteinENSG0000026170118
F7 / P08709 / coagulation factor VIIENSG0000005759318
PROZ / P22891 / protein Z, vitamin K dependent plasma glycoproteinENSG0000012623114


Protein motifs (from Interpro)
Interpro ID Name
 IPR000859  CUB domain
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR033116  Serine proteases, trypsin family, serine active site
 IPR035914  Spermadhesin, CUB domain superfamily
 IPR035976  Sushi/SCR/CCP superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006958 complement activation, classical pathway IEA
 biological_processGO:0045087 innate immune response IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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