ENSG00000261701


Homo sapiens

Features
Gene ID: ENSG00000261701
  
Biological name :HPR
  
Synonyms : haptoglobin-related protein / HPR / P00739
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q22.2
Gene start: 72063224
Gene end: 72077246
  
Corresponding Affymetrix probe sets: 208470_s_at (Human Genome U133 Plus 2.0 Array)   208471_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000441828
Ensembl peptide - ENSP00000462916
Ensembl peptide - ENSP00000349451
NCBI entrez gene - 3250     See in Manteia.
OMIM - 140210
RefSeq - NM_020995
RefSeq Peptide - NP_066275
swissprot - A0A0A0MRD9
swissprot - J3KTC3
swissprot - P00739
Ensembl - ENSG00000261701
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hpENSDARG00000051890Danio rerio
 HpENSMUSG00000031722Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HP / P00738 / haptoglobinENSG0000025701791
C1S / P09871 / complement C1sENSG0000018232632
C1R / P00736 / complement C1rENSG0000015940332
MASP1 / P48740 / mannan binding lectin serine peptidase 1ENSG0000012724131
MASP2 / O00187 / mannan binding lectin serine peptidase 2ENSG0000000972429
C1RL / Q9NZP8 / complement C1r subcomponent likeENSG0000013917825
F10 / P00742 / coagulation factor XENSG0000012621822
F9 / P00740 / coagulation factor IXENSG0000010198122
F7 / P08709 / coagulation factor VIIENSG0000005759322
PAMR1 / Q6UXH9 / peptidase domain containing associated with muscle regeneration 1ENSG0000014909020
PROC / P04070 / protein C, inactivator of coagulation factors Va and VIIIaENSG0000011571820
PROZ / P22891 / protein Z, vitamin K dependent plasma glycoproteinENSG0000012623115


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR008292  Haptoglobin
 IPR009003  Peptidase S1, PA clan
 IPR035976  Sushi/SCR/CCP superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006898 receptor-mediated endocytosis TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0034366 spherical high-density lipoprotein particle IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0072562 blood microparticle HDA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0030492 hemoglobin binding NAS


Pathways (from Reactome)
Pathway description
Scavenging of heme from plasma


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000261701 HPR / P00739 / haptoglobin-related protein  / complex






 

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