ENSG00000143257


Homo sapiens

Features
Gene ID: ENSG00000143257
  
Biological name :NR1I3
  
Synonyms : NR1I3 / nuclear receptor subfamily 1 group I member 3 / Q14994
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q23.3
Gene start: 161229666
Gene end: 161238302
  
Corresponding Affymetrix probe sets: 1570188_at (Human Genome U133 Plus 2.0 Array)   207007_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000426292
Ensembl peptide - ENSP00000426016
Ensembl peptide - ENSP00000427034
Ensembl peptide - ENSP00000487337
Ensembl peptide - ENSP00000427600
Ensembl peptide - ENSP00000427175
Ensembl peptide - ENSP00000356958
Ensembl peptide - ENSP00000356959
Ensembl peptide - ENSP00000356960
Ensembl peptide - ENSP00000356961
Ensembl peptide - ENSP00000356962
Ensembl peptide - ENSP00000356963
Ensembl peptide - ENSP00000356965
Ensembl peptide - ENSP00000399361
Ensembl peptide - ENSP00000406493
Ensembl peptide - ENSP00000407446
Ensembl peptide - ENSP00000412672
Ensembl peptide - ENSP00000421374
Ensembl peptide - ENSP00000421588
Ensembl peptide - ENSP00000422982
Ensembl peptide - ENSP00000423007
Ensembl peptide - ENSP00000423089
Ensembl peptide - ENSP00000423666
Ensembl peptide - ENSP00000424345
Ensembl peptide - ENSP00000424834
Ensembl peptide - ENSP00000424934
Ensembl peptide - ENSP00000425417
Ensembl peptide - ENSP00000425607
Ensembl peptide - ENSP00000425900
NCBI entrez gene - 9970     See in Manteia.
OMIM - 603881
RefSeq - NM_001077480
RefSeq - NM_001077469
RefSeq - NM_001077470
RefSeq - NM_001077471
RefSeq - NM_001077472
RefSeq - NM_001077473
RefSeq - NM_001077474
RefSeq - NM_001077475
RefSeq - NM_001077476
RefSeq - NM_001077477
RefSeq - NM_001077478
RefSeq - NM_001077479
RefSeq - NM_001077481
RefSeq - NM_001077482
RefSeq - NM_005122
RefSeq - XM_005245693
RefSeq - XM_005245694
RefSeq - XM_005245697
RefSeq - XM_011510237
RefSeq Peptide - NP_001070937
RefSeq Peptide - NP_001070938
RefSeq Peptide - NP_001070939
RefSeq Peptide - NP_001070940
RefSeq Peptide - NP_001070941
RefSeq Peptide - NP_001070942
RefSeq Peptide - NP_001070943
RefSeq Peptide - NP_001070944
RefSeq Peptide - NP_001070945
RefSeq Peptide - NP_001070946
RefSeq Peptide - NP_001070947
RefSeq Peptide - NP_001070948
RefSeq Peptide - NP_001070949
RefSeq Peptide - NP_001070950
RefSeq Peptide - NP_005113
swissprot - E9PCF2
swissprot - D6REZ7
swissprot - C0H5Y2
swissprot - Q6GZ70
swissprot - Q6GZ72
swissprot - Q6GZ81
swissprot - Q14994
swissprot - Q6GZ69
swissprot - B7Z8R7
Ensembl - ENSG00000143257
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Nr1i3ENSMUSG00000005677Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NR1I2 / O75469 / nuclear receptor subfamily 1 group I member 2ENSG0000014485246
VDR / P11473 / vitamin D receptorENSG0000011142439
NR1H3 / Q13133 / nuclear receptor subfamily 1 group H member 3ENSG0000002543431
NR1H2 / P55055 / nuclear receptor subfamily 1 group H member 2ENSG0000013140831
THRB / P10828 / thyroid hormone receptor betaENSG0000015109029
RARA / P10276 / retinoic acid receptor alphaENSG0000013175929
THRA / P10827 / thyroid hormone receptor, alphaENSG0000012635129
NR1H4 / Q96RI1 / nuclear receptor subfamily 1 group H member 4ENSG0000001250429
RARG / P13631 / retinoic acid receptor gammaENSG0000017281927
RARB / P10826 / retinoic acid receptor betaENSG0000007709227


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR001728  Thyroid hormone receptor
 IPR013088  Zinc finger, NHR/GATA-type
 IPR035500  Nuclear hormone receptor-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0030521 androgen receptor signaling pathway IEA
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0003713 transcription coactivator activity TAS
 molecular_functionGO:0004879 nuclear receptor activity TAS
 molecular_functionGO:0004882 androgen receptor activity TAS
 molecular_functionGO:0004887 thyroid hormone receptor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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