ENSG00000151490
Homo sapiens | |
Features
| Gene ID: | ENSG00000151490 | | | | | Biological name : | PTPRO | | | | | Synonyms : | protein tyrosine phosphatase, receptor type O / PTPRO / Q16827 | | | | | Possible biological names infered from orthology : | | | | | | Species: | Homo sapiens | | | | | Chr. number: | 12 | | Strand: | 1 | | Band: | p12.3 | | Gene start: | 15322397 | | Gene end: | 15597399 | | | | | Corresponding Affymetrix probe sets: | 1554199_at (Human Genome U133 Plus 2.0 Array) 208121_s_at (Human Genome U133 Plus 2.0 Array) | | | | | Cross references: | Ensembl peptide - ENSP00000444173
Ensembl peptide - ENSP00000439234
Ensembl peptide - ENSP00000445621
Ensembl peptide - ENSP00000446201
Ensembl peptide - ENSP00000281171
Ensembl peptide - ENSP00000343434
Ensembl peptide - ENSP00000393449
Ensembl peptide - ENSP00000404188
Ensembl peptide - ENSP00000437571
NCBI entrez gene - 5800
See in Manteia.
OMIM - 600579
RefSeq - XM_017019725
RefSeq - NM_002848
RefSeq - NM_030667
RefSeq - NM_030668
RefSeq - NM_030669
RefSeq - NM_030670
RefSeq - NM_030671
RefSeq Peptide - NP_109596
RefSeq Peptide - NP_002839
RefSeq Peptide - NP_109592
RefSeq Peptide - NP_109593
RefSeq Peptide - NP_109594
RefSeq Peptide - NP_109595
swissprot - Q16827
swissprot - A0A024RAS0
swissprot - H0YH11
swissprot - H0YH60
swissprot - A0A024RAS9
Ensembl - ENSG00000151490
| | | | | Related genetic diseases (OMIM): | 614196 - Nephrotic syndrome, type 6, 614196 |
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed
Ortholog prediction (from Ensembl)
Paralog prediction (from Ensembl)
| PTPRB / P23467 / protein tyrosine phosphatase, receptor type B | ENSG00000127329 | 28 | | PTPRQ / protein tyrosine phosphatase, receptor type Q | ENSG00000139304 | 21 | | PTPRJ / Q12913 / protein tyrosine phosphatase, receptor type J | ENSG00000149177 | 20 | | PTPRH / Q9HD43 / protein tyrosine phosphatase, receptor type H | ENSG00000080031 | 19 | | PTPN9 / P43378 / protein tyrosine phosphatase, non-receptor type 9 | ENSG00000169410 | 10 | | PTPN20 / Q4JDL3 / protein tyrosine phosphatase, non-receptor type 20 | ENSG00000204179 | 9 | | PTPN12 / Q05209 / protein tyrosine phosphatase, non-receptor type 12 | ENSG00000127947 | 8 | | PTPN1 / P18031 / protein tyrosine phosphatase, non-receptor type 1 | ENSG00000196396 | 8 | | PTPN22 / Q9Y2R2 / protein tyrosine phosphatase, non-receptor type 22 | ENSG00000134242 | 8 | | PTPN18 / Q99952 / protein tyrosine phosphatase, non-receptor type 18 | ENSG00000072135 | 8 | | PTPN2 / P17706 / protein tyrosine phosphatase, non-receptor type 2 | ENSG00000175354 | 8 |
Protein motifs (from Interpro)
Gene Ontology (GO)
Pathways (from Reactome)
Phenotype (from MGI, Zfin or HPO)
| HP:0000007 | Autosomal recessive inheritance | "A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in homozygotes. In the context of medical genetics, autosomal recessive disorders manifest in homozygotes (with two copies of the mutant allele) or compound heterozygotes (whereby each copy of a gene has a distinct mutant allele)." [HPO:curators] |
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| | HP:0000093 | Proteinuria | |
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| | HP:0000097 | Focal segmental glomerulosclerosis | |
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| | HP:0000100 | Nephrotic syndrome | |
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| | HP:0000969 | Edema | "An abnormal accumulation of fluid beneath the skin, or in one or more cavities of the body. Edema may be related to one or more of the following factors: 1) increased capillary hydrostatic pressure, 2) decreased osmotic pressure of plasma, 3) decreased tissue tension and lymphatic drainage, 4) increased osmotic pressure of tissue fluids, and 5) increased capillary permeability." [HPO:curators] |
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| | HP:0003073 | Hypoalbuminemia | "Reduction in the concentration of albumin in the blood." [HPO:curators] |
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| | HP:0003828 | Variable expressivity | |
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| | HP:0005576 | Tubulointerstitial fibrosis | |
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Interacting proteins (from Reactome)
No match
0 s.
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