ENSG00000169410


Homo sapiens

Features
Gene ID: ENSG00000169410
  
Biological name :PTPN9
  
Synonyms : P43378 / protein tyrosine phosphatase, non-receptor type 9 / PTPN9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q24.2
Gene start: 75463251
Gene end: 75579289
  
Corresponding Affymetrix probe sets: 202958_at (Human Genome U133 Plus 2.0 Array)   230140_at (Human Genome U133 Plus 2.0 Array)   233226_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000303554
Ensembl peptide - ENSP00000482732
Ensembl peptide - ENSP00000455934
NCBI entrez gene - 5780     See in Manteia.
OMIM - 600768
RefSeq - NM_002833
RefSeq Peptide - NP_002824
swissprot - A0A0A0MR09
swissprot - H3BQT6
swissprot - P43378
Ensembl - ENSG00000169410
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptpn9aENSDARG00000077495Danio rerio
 PTPN9ENSGALG00000001664Gallus gallus
 Ptpn9ENSMUSG00000032290Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTPRB / P23467 / protein tyrosine phosphatase, receptor type BENSG0000012732927
PTPRH / Q9HD43 / protein tyrosine phosphatase, receptor type HENSG0000008003126
PTPRJ / Q12913 / protein tyrosine phosphatase, receptor type JENSG0000014917725
PTPRQ / protein tyrosine phosphatase, receptor type QENSG0000013930422
PTPRO / Q16827 / protein tyrosine phosphatase, receptor type OENSG0000015149021
PTPN2 / P17706 / protein tyrosine phosphatase, non-receptor type 2ENSG0000017535418
PTPN18 / Q99952 / protein tyrosine phosphatase, non-receptor type 18ENSG0000007213518
PTPN20 / Q4JDL3 / protein tyrosine phosphatase, non-receptor type 20ENSG0000020417918
PTPN1 / P18031 / protein tyrosine phosphatase, non-receptor type 1ENSG0000019639618
PTPN12 / Q05209 / protein tyrosine phosphatase, non-receptor type 12ENSG0000012794717
PTPN22 / Q9Y2R2 / protein tyrosine phosphatase, non-receptor type 22ENSG0000013424216


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR001251  CRAL-TRIO lipid binding domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR011074  CRAL/TRIO, N-terminal domain
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like
 IPR036273  CRAL/TRIO, N-terminal domain superfamily
 IPR036865  CRAL-TRIO lipid binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0010977 negative regulation of neuron projection development IDA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0071345 cellular response to cytokine stimulus TAS
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0044306 neuron projection terminus IDA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0004726 non-membrane spanning protein tyrosine phosphatase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Interleukin-37 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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