ENSG00000157514


Homo sapiens

Features
Gene ID: ENSG00000157514
  
Biological name :TSC22D3
  
Synonyms : Q99576 / TSC22D3 / TSC22 domain family member 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: q22.3
Gene start: 107713221
Gene end: 107777342
  
Corresponding Affymetrix probe sets: 207001_x_at (Human Genome U133 Plus 2.0 Array)   208763_s_at (Human Genome U133 Plus 2.0 Array)   235364_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361474
Ensembl peptide - ENSP00000427427
Ensembl peptide - ENSP00000427199
Ensembl peptide - ENSP00000427075
Ensembl peptide - ENSP00000425414
Ensembl peptide - ENSP00000425158
Ensembl peptide - ENSP00000425155
Ensembl peptide - ENSP00000424653
Ensembl peptide - ENSP00000422636
Ensembl peptide - ENSP00000422228
Ensembl peptide - ENSP00000422060
Ensembl peptide - ENSP00000421016
Ensembl peptide - ENSP00000314655
Ensembl peptide - ENSP00000361457
Ensembl peptide - ENSP00000361458
Ensembl peptide - ENSP00000361459
Ensembl peptide - ENSP00000361466
NCBI entrez gene - 1831     See in Manteia.
OMIM - 300506
RefSeq - XM_017029335
RefSeq - NM_001015881
RefSeq - NM_001318468
RefSeq - NM_001318470
RefSeq - NM_004089
RefSeq - NM_198057
RefSeq - XM_005262099
RefSeq - XM_005262100
RefSeq - XM_005262102
RefSeq - XM_005262103
RefSeq - XM_011530884
RefSeq Peptide - NP_001305397
RefSeq Peptide - NP_001305399
RefSeq Peptide - NP_004080
RefSeq Peptide - NP_001015881
RefSeq Peptide - NP_932174
swissprot - Q5JRJ0
swissprot - D6RD37
swissprot - D6RCK9
swissprot - D6RBL1
swissprot - D6RAX8
swissprot - D6R9J1
swissprot - D6R8Z7
swissprot - D6RDZ9
swissprot - D6RD92
swissprot - Q5JRJ2
swissprot - Q99576
swissprot - E7EWD5
swissprot - D6RDZ7
Ensembl - ENSG00000157514
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-220e11.3ENSDARG00000105498Danio rerio
 tsc22d3ENSDARG00000075666Danio rerio
 TSC22D3ENSGALG00000027069Gallus gallus
 Q9Z2S7ENSMUSG00000031431Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O75157 / TSC22D2 / TSC22 domain family member 2ENSG0000019642845
Q15714 / TSC22D1 / TSC22 domain family member 1ENSG0000010280445
Q9Y3Q8 / TSC22D4 / TSC22 domain family member 4ENSG0000016692533


Protein motifs (from Interpro)
Interpro ID Name
 IPR000580  TSC-22 / Dip / Bun


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006970 response to osmotic stress IEA
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:0048642 negative regulation of skeletal muscle tissue development IEA
 biological_processGO:0070236 negative regulation of activation-induced cell death of T cells IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043426 MRF binding IEA


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000132155 RAF1 / P04049 / Raf-1 proto-oncogene, serine/threonine kinase  / complex
 ENSG00000123124 WWP1 / Q9H0M0 / WW domain containing E3 ubiquitin protein ligase 1  / complex
 ENSG00000118515 SGK1 / O00141 / serum/glucocorticoid regulated kinase 1  / complex
 ENSG00000101049 SGK2 / Q9HBY8 / SGK2, serine/threonine kinase 2  / complex
 ENSG00000104205 SGK3 / Q96BR1 / serum/glucocorticoid regulated kinase family member 3  / complex
 ENSG00000049759 NEDD4L / Q96PU5 / neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase  / complex






 

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