ENSG00000160191


Homo sapiens

Features
Gene ID: ENSG00000160191
  
Biological name :PDE9A
  
Synonyms : O76083 / PDE9A / phosphodiesterase 9A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: 1
Band: q22.3
Gene start: 42653636
Gene end: 42775509
  
Corresponding Affymetrix probe sets: 205593_s_at (Human Genome U133 Plus 2.0 Array)   237139_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000381285
Ensembl peptide - ENSP00000381283
Ensembl peptide - ENSP00000381287
Ensembl peptide - ENSP00000381291
Ensembl peptide - ENSP00000381289
Ensembl peptide - ENSP00000291539
Ensembl peptide - ENSP00000328699
Ensembl peptide - ENSP00000335242
Ensembl peptide - ENSP00000335365
Ensembl peptide - ENSP00000344730
Ensembl peptide - ENSP00000369685
Ensembl peptide - ENSP00000381280
Ensembl peptide - ENSP00000381281
NCBI entrez gene - 5152     See in Manteia.
OMIM - 602973
RefSeq - NM_001001573
RefSeq - NM_001001567
RefSeq - NM_001001568
RefSeq - NM_001001569
RefSeq - NM_001001570
RefSeq - NM_001001571
RefSeq - NM_001001572
RefSeq - NM_001001574
RefSeq - NM_001001575
RefSeq - NM_001001576
RefSeq - NM_001001577
RefSeq - NM_001001578
RefSeq - NM_001001579
RefSeq - NM_001001580
RefSeq - NM_001001581
RefSeq - NM_001001582
RefSeq - NM_001001583
RefSeq - NM_001001584
RefSeq - NM_001001585
RefSeq - NM_001315533
RefSeq - NM_002606
RefSeq - XM_011529598
RefSeq - XM_011529600
RefSeq - XM_017028366
RefSeq Peptide - NP_001001567
RefSeq Peptide - NP_001001568
RefSeq Peptide - NP_001001584
RefSeq Peptide - NP_001001585
RefSeq Peptide - NP_001302462
RefSeq Peptide - NP_002597
RefSeq Peptide - NP_001001569
RefSeq Peptide - NP_001001570
RefSeq Peptide - NP_001001571
RefSeq Peptide - NP_001001572
RefSeq Peptide - NP_001001573
RefSeq Peptide - NP_001001574
RefSeq Peptide - NP_001001575
RefSeq Peptide - NP_001001576
RefSeq Peptide - NP_001001577
RefSeq Peptide - NP_001001578
RefSeq Peptide - NP_001001579
RefSeq Peptide - NP_001001580
RefSeq Peptide - NP_001001581
RefSeq Peptide - NP_001001582
RefSeq Peptide - NP_001001583
swissprot - A0A0S2Z4T6
swissprot - A0A0S2Z4A3
swissprot - A0A0S2Z475
swissprot - O76083
Ensembl - ENSG00000160191
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FQ378016.1ENSDARG00000108939Danio rerio
 pde9aENSDARG00000060280Danio rerio
 pde9alENSDARG00000076650Danio rerio
 PDE9AENSGALG00000016186Gallus gallus
 Pde9aENSMUSG00000041119Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDE6B / P35913 / phosphodiesterase 6BENSG0000013325623
PDE6A / P16499 / phosphodiesterase 6AENSG0000013291522
PDE11A / Q9HCR9 / phosphodiesterase 11AENSG0000012865521
PDE5A / O76074 / phosphodiesterase 5AENSG0000013873521
PDE6C / P51160 / phosphodiesterase 6CENSG0000009546421
PDE2A / O00408 / phosphodiesterase 2AENSG0000018664221
PDE11A / phosphodiesterase 11AENSG0000028474120
PDE3A / Q14432 / phosphodiesterase 3AENSG0000017257220
PDE3B / Q13370 / phosphodiesterase 3BENSG0000015227020
PDE10A / Q9Y233 / phosphodiesterase 10AENSG0000011254118


Protein motifs (from Interpro)
Interpro ID Name
 IPR002073  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain
 IPR003607  HD/PDEase domain
 IPR023088  3"5"-cyclic nucleotide phosphodiesterase
 IPR023174  3"5"-cyclic nucleotide phosphodiesterase, conserved site
 IPR036971  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0010613 positive regulation of cardiac muscle hypertrophy ISS
 biological_processGO:0019934 cGMP-mediated signaling IEA
 biological_processGO:0046068 cGMP metabolic process IDA
 biological_processGO:0046069 cGMP catabolic process IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0032587 ruffle membrane IEA
 cellular_componentGO:0042383 sarcolemma IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043204 perikaryon IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0004114 3",5"-cyclic-nucleotide phosphodiesterase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047555 3",5"-cyclic-GMP phosphodiesterase activity IEA


Pathways (from Reactome)
Pathway description
cGMP effects


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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