ENSG00000167157


Homo sapiens

Features
Gene ID: ENSG00000167157
  
Biological name :PRRX2
  
Synonyms : paired related homeobox 2 / PRRX2 / Q99811
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q34.11
Gene start: 129665641
Gene end: 129722674
  
Corresponding Affymetrix probe sets: 219729_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361547
NCBI entrez gene - 51450     See in Manteia.
OMIM - 604675
RefSeq - NM_016307
RefSeq Peptide - NP_057391
swissprot - A0A140VJS2
swissprot - Q99811
Ensembl - ENSG00000167157
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PRRX2ENSGALG00000028236Gallus gallus
 Prrx2ENSMUSG00000039476Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRRX1 / P54821 / paired related homeobox 1ENSG0000011613258
PITX3 / O75364 / paired like homeodomain 3ENSG0000010785930
PITX1 / P78337 / paired like homeodomain 1ENSG0000006901129
PITX2 / Q99697 / paired like homeodomain 2ENSG0000016409329
OTX2 / P32243 / orthodenticle homeobox 2ENSG0000016558826
DMBX1 / Q8NFW5 / diencephalon/mesencephalon homeobox 1ENSG0000019758725
OTX1 / P32242 / orthodenticle homeobox 1ENSG0000011550725
PROP1 / O75360 / PROP paired-like homeobox 1ENSG0000017532524
GSC2 / O15499 / goosecoid homeobox 2ENSG0000006351521
CRX / O43186 / cone-rod homeoboxENSG0000010539221
MIXL1 / Q9H2W2 / Mix paired-like homeoboxENSG0000018515520
GSC / P56915 / goosecoid homeoboxENSG0000013393718


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR003654  OAR domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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