ENSG00000167578


Homo sapiens

Features
Gene ID: ENSG00000167578
  
Biological name :RAB4B
  
Synonyms : P61018 / RAB4B / RAB4B, member RAS oncogene family
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.2
Gene start: 40778216
Gene end: 40796938
  
Corresponding Affymetrix probe sets: 219807_x_at (Human Genome U133 Plus 2.0 Array)   228521_s_at (Human Genome U133 Plus 2.0 Array)   233385_x_at (Human Genome U133 Plus 2.0 Array)   237257_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000367557
Ensembl peptide - ENSP00000471504
Ensembl peptide - ENSP00000470246
Ensembl peptide - ENSP00000349560
NCBI entrez gene - 53916     See in Manteia.
OMIM - 612945
RefSeq - NM_016154
RefSeq Peptide - NP_057238
swissprot - M0R0X1
swissprot - A0A024R0K8
swissprot - P61018
swissprot - Q6PIK3
Ensembl - ENSG00000167578
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab4bENSDARG00000012177Danio rerio
 Rab4bENSMUSG00000053291Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAB4B-EGLN2 / RAB4B-EGLN2 readthrough (NMD candidate)ENSG00000171570100
RAB4A / P20338 / RAB4A, member RAS oncogene familyENSG0000016811887
RAB14 / P61106 / RAB14, member RAS oncogene familyENSG0000011939659
RAB2B / Q8WUD1 / RAB2B, member RAS oncogene familyENSG0000012947253
RAB2A / P61019 / RAB2A, member RAS oncogene familyENSG0000010438851
Q15907 / RAB11B / RAB11B, member RAS oncogene familyENSG0000018523645
P62491 / RAB11A / RAB11A, member RAS oncogene familyENSG0000010376944
RAB25 / P57735 / RAB25, member RAS oncogene familyENSG0000013269843
Q14964 / RAB39A / RAB39A, member RAS oncogene familyENSG0000017933140
Q96DA2 / RAB39B / RAB39B, member RAS oncogene familyENSG0000015596140
RAB18 / Q9NP72 / RAB18, member RAS oncogene familyENSG0000009924637
RAB42 / Q8N4Z0 / RAB42, member RAS oncogene familyENSG0000018806013


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0030100 regulation of endocytosis IBA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0046323 glucose import IMP
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030667 secretory granule membrane TAS
 cellular_componentGO:0032593 insulin-responsive compartment IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0055037 recycling endosome IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
RAB geranylgeranylation
MET receptor recycling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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