ENSG00000179331


Homo sapiens

Features
Gene ID: ENSG00000179331
  
Biological name :RAB39A
  
Synonyms : Q14964 / RAB39A / RAB39A, member RAS oncogene family
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q22.3
Gene start: 107928503
Gene end: 107963482
  
Corresponding Affymetrix probe sets: 1554800_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000322594
NCBI entrez gene - 54734     See in Manteia.
RefSeq - NM_017516
RefSeq Peptide - NP_059986
swissprot - Q14964
Ensembl - ENSG00000179331
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAB39AENSGALG00000017166Gallus gallus
 Rab39ENSMUSG00000055069Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96DA2 / RAB39B / RAB39B, member RAS oncogene familyENSG0000015596177
RAB2B / Q8WUD1 / RAB2B, member RAS oncogene familyENSG0000012947244
RAB2A / P61019 / RAB2A, member RAS oncogene familyENSG0000010438843
RAB4B / P61018 / RAB4B, member RAS oncogene familyENSG0000016757840
RAB4B-EGLN2 / RAB4B-EGLN2 readthrough (NMD candidate)ENSG0000017157040
RAB4A / P20338 / RAB4A, member RAS oncogene familyENSG0000016811839
RAB14 / P61106 / RAB14, member RAS oncogene familyENSG0000011939639
Q15907 / RAB11B / RAB11B, member RAS oncogene familyENSG0000018523638
P62491 / RAB11A / RAB11A, member RAS oncogene familyENSG0000010376938
RAB18 / Q9NP72 / RAB18, member RAS oncogene familyENSG0000009924635
RAB25 / P57735 / RAB25, member RAS oncogene familyENSG0000013269835
RAB42 / Q8N4Z0 / RAB42, member RAS oncogene familyENSG0000018806018


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0090383 phagosome acidification IMP
 biological_processGO:0090385 phagosome-lysosome fusion IMP
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030670 phagocytic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045335 phagocytic vesicle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding NAS


Pathways (from Reactome)
Pathway description
Intra-Golgi traffic
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000184014 Q6IQ26 / DENND5A / DENN domain containing 5A  / reaction
 ENSG00000170456 Q6ZUT9 / DENND5B / DENN domain containing 5B  / reaction
 ENSG00000188419 CHM / P24386 / CHM, Rab escort protein 1  / complex
 ENSG00000203668 CHML / P26374 / CHM like, Rab escort protein 2  / complex
 ENSG00000057608 GDI2 / P50395 / GDP dissociation inhibitor 2  / complex
 ENSG00000203879 GDI1 / P31150 / GDP dissociation inhibitor 1  / complex






 

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