Manteia

ENSMUSG00000055069

Mus musculus

Features

Gene ID:	ENSMUSG00000055069

Biological name :	Rab39

Synonyms :	Q8BHD0 / Rab39 / RAB39, member RAS oncogene family

Possible biological names infered from orthology :	Q14964 / RAB39A / RAB39A, member RAS oncogene family

Species:	Mus musculus

Chr. number:	9
Strand:	-1
Band:	A5.3
Gene start:	53684110
Gene end:	53706232

Corresponding Affymetrix probe sets:	10593628 (MoGene1.0st) 1437762_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000063804 NCBI entrez gene - 270160 See in Manteia. MGI - MGI:2442855 RefSeq - NM_175562 RefSeq Peptide - NP_780771 swissprot - Q0PD15 swissprot - Q8BHD0 Ensembl - ENSMUSG00000055069

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Q8BHC1 / Rab39b / RAB39B, member RAS oncogene family / Q96DA2*	ENSMUSG00000031202	76
Rab42 / Q0PD08 / Ras-related protein Rab-42 / Q8N4Z0* / RAB42, member RAS oncogene family*	ENSMUSG00000089687	46
Rab2a / P53994 / Ras-related protein Rab-2A / P61019* / RAB2A, member RAS oncogene family*	ENSMUSG00000047187	44
Rab2b / P59279 / RAB2B, member RAS oncogene family / Q8WUD1*	ENSMUSG00000022159	43
Rab4b / Q91ZR1 / RAB4B, member RAS oncogene family / P61018* / RAB4B-EGLN2* / RAB4B-EGLN2 readthrough (NMD candidate)*	ENSMUSG00000053291	40
Rab4a / P56371 / Ras-related protein Rab-4A / P20338* / RAB4A, member RAS oncogene family*	ENSMUSG00000019478	39
Rab14 / Q91V41 / RAB14, member RAS oncogene family / P61106*	ENSMUSG00000026878	38
P62492 / Rab11a / RAB11A, member RAS oncogene family / P62491*	ENSMUSG00000004771	38
P46638 / Rab11b / RAB11B, member RAS oncogene family / Q15907*	ENSMUSG00000077450	38
Rab25 / Q9WTL2 / RAB25, member RAS oncogene family / P57735*	ENSMUSG00000008601	35
Rab18 / P35293 / RAB18, member RAS oncogene family / Q9NP72*	ENSMUSG00000073639	34

Protein motifs (from Interpro)

Interpro ID	Name
IPR001806	Small GTPase superfamily
IPR005225	Small GTP-binding protein domain
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006914	autophagy	IEA
biological_process	GO:0015031	protein transport	IEA
biological_process	GO:0090383	phagosome acidification	IEA
biological_process	GO:0090385	phagosome-lysosome fusion	IEA
cellular_component	GO:0005764	lysosome	IEA
cellular_component	GO:0005794	Golgi apparatus	IBA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0030670	phagocytic vesicle membrane	IEA
cellular_component	GO:0031410	cytoplasmic vesicle	IEA
cellular_component	GO:0045335	phagocytic vesicle	ISS
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0003924	GTPase activity	IEA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0005525	GTP binding	IEA

Pathways (from Reactome)

Pathway description

Intra-Golgi traffic

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0005627	increased circulating potassium level	"greater than the normal concentration in the blood of this alkaline metallic element, the most abundant intracellular ion; anomalies in the extracellular (circulating) concentration have important implications for the function of excitable tissues, such as nerve and muscle" [RGD:Rat Genome Database submission]	Show Allelic Composition: Enho^tm1.1Butl/Enho⁺ Genetic Background: B6.Cg-Enho^tm1.1Butl

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000025531	Chm / choroidermia (RAB escort protein 1) / P24386* / CHM, Rab escort protein 1*	/ complex
ENSMUSG00000021218	Gdi2 / Q61598 / Rab GDP dissociation inhibitor beta / P50395* / GDP dissociation inhibitor 2*	/ complex
ENSMUSG00000015291	Gdi1 / P50396 / Rab GDP dissociation inhibitor alpha / P31150* / GDP dissociation inhibitor 1*	/ complex
ENSMUSG00000078185	Chml / choroideremia-like / P26374* / CHM like, Rab escort protein 2*	/ complex
ENSMUSG00000035901	Q6PAL8 / Dennd5a / DENN domain-containing protein 5A / Q6IQ26* / DENN domain containing 5A*	/ reaction
ENSMUSG00000030313	A2RSQ0 / Dennd5b / DENN domain-containing protein 5B / Q6ZUT9* / DENN domain containing 5B*	/ reaction

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr