ENSMUSG00000026878


Mus musculus

Features
Gene ID: ENSMUSG00000026878
  
Biological name :Rab14
  
Synonyms : Q91V41 / Rab14 / RAB14, member RAS oncogene family
  
Possible biological names infered from orthology : P61106
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: B
Gene start: 35180205
Gene end: 35201120
  
Corresponding Affymetrix probe sets: 10482017 (MoGene1.0st)   10338498 (MoGene1.0st)   10339198 (MoGene1.0st)   10339426 (MoGene1.0st)   10341376 (MoGene1.0st)   10341652 (MoGene1.0st)   10341779 (MoGene1.0st)   10342383 (MoGene1.0st)   10342702 (MoGene1.0st)   10343132 (MoGene1.0st)   10343535 (MoGene1.0st)   10343918 (MoGene1.0st)   10338153 (MoGene1.0st)   10338198 (MoGene1.0st)   10338349 (MoGene1.0st)   10338611 (MoGene1.0st)   10338745 (MoGene1.0st)   10338851 (MoGene1.0st)   10338978 (MoGene1.0st)   10339564 (MoGene1.0st)   10339784 (MoGene1.0st)   10339888 (MoGene1.0st)   10339909 (MoGene1.0st)   10340156 (MoGene1.0st)   10340521 (MoGene1.0st)   10340583 (MoGene1.0st)   10340670 (MoGene1.0st)   10340921 (MoGene1.0st)   10341033 (MoGene1.0st)   10341131 (MoGene1.0st)   10341153 (MoGene1.0st)   10341180 (MoGene1.0st)   10341568 (MoGene1.0st)   10341683 (MoGene1.0st)   10341879 (MoGene1.0st)   10342133 (MoGene1.0st)   10342542 (MoGene1.0st)   10342921 (MoGene1.0st)   10343296 (MoGene1.0st)   10343458 (MoGene1.0st)   10343506 (MoGene1.0st)   10343513 (MoGene1.0st)   10343524 (MoGene1.0st)   10344174 (MoGene1.0st)   10344387 (MoGene1.0st)   10344571 (MoGene1.0st)   10344575 (MoGene1.0st)   1415686_at (Mouse Genome 430 2.0 Array)   1419243_at (Mouse Genome 430 2.0 Array)   1419244_a_at (Mouse Genome 430 2.0 Array)   1419245_at (Mouse Genome 430 2.0 Array)   1419246_s_at (Mouse Genome 430 2.0 Array)   1439687_at (Mouse Genome 430 2.0 Array)   1441992_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028238
Ensembl peptide - ENSMUSP00000155278
Ensembl peptide - ENSMUSP00000155540
NCBI entrez gene - 68365     See in Manteia.
MGI - MGI:1915615
RefSeq - NM_026697
RefSeq Peptide - NP_080973
swissprot - Q50HX3
swissprot - Q50HX4
swissprot - Q91V41
Ensembl - ENSMUSG00000026878
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab14ENSDARG00000074246Danio rerio
 RAB14ENSGALG00000001474Gallus gallus
 RAB14ENSG00000119396Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rab4a / P56371 / Ras-related protein Rab-4A / P20338* / RAB4A, member RAS oncogene family*ENSMUSG0000001947859
Rab4b / Q91ZR1 / RAB4B, member RAS oncogene family / P61018* / RAB4B-EGLN2* / RAB4B-EGLN2 readthrough (NMD candidate)*ENSMUSG0000005329158
Rab2a / P53994 / Ras-related protein Rab-2A / P61019* / RAB2A, member RAS oncogene family*ENSMUSG0000004718755
Rab2b / P59279 / RAB2B, member RAS oncogene family / Q8WUD1*ENSMUSG0000002215954
P46638 / Rab11b / RAB11B, member RAS oncogene family / Q15907*ENSMUSG0000007745043
P62492 / Rab11a / RAB11A, member RAS oncogene family / P62491*ENSMUSG0000000477143
Rab25 / Q9WTL2 / RAB25, member RAS oncogene family / P57735*ENSMUSG0000000860141
Rab18 / P35293 / RAB18, member RAS oncogene family / Q9NP72*ENSMUSG0000007363939
Rab39 / Q8BHD0 / RAB39, member RAS oncogene family / Q14964* / RAB39A* / RAB39A, member RAS oncogene family*ENSMUSG0000005506939
Q8BHC1 / Rab39b / RAB39B, member RAS oncogene family / Q96DA2*ENSMUSG0000003120236
Rab42 / Q0PD08 / Ras-related protein Rab-42 / Q8N4Z0* / RAB42, member RAS oncogene family*ENSMUSG0000008968735


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030702  Ras-related protein Rab14


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006895 Golgi to endosome transport IEA
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway IMP
 biological_processGO:0009790 embryo development IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0030100 regulation of endocytosis IBA
 biological_processGO:0032456 endocytic recycling IEA
 biological_processGO:0032880 regulation of protein localization IEA
 biological_processGO:0042742 defense response to bacterium IEA
 biological_processGO:0090382 phagosome maturation IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005768 endosome IBA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane TAS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0045335 phagocytic vesicle IEA
 cellular_componentGO:0055037 recycling endosome IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0019003 GDP binding IEA
 molecular_functionGO:0031489 myosin V binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane
Neutrophil degranulation
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000015291 Gdi1 / P50396 / Rab GDP dissociation inhibitor alpha / P31150* / GDP dissociation inhibitor 1*  / complex
 ENSMUSG00000017831 Rab5a / Q9CQD1 / Ras-related protein Rab-5A / P20339* / RAB5A, member RAS oncogene family*  / reaction / complex
 ENSMUSG00000020375 Rufy1 / Q8BIJ7 / RUN and FYVE domain-containing protein 1 / Q96T51* / RUN and FYVE domain containing 1*  / reaction / complex
 ENSMUSG00000025531 Chm / choroidermia (RAB escort protein 1) / P24386* / CHM, Rab escort protein 1*  / complex
 ENSMUSG00000040818 Q8BH65 / Dennd6a / Protein DENND6A / Q8IWF6* / DENN domain containing 6A*  / reaction
 ENSMUSG00000021218 Gdi2 / Q61598 / Rab GDP dissociation inhibitor beta / P50395* / GDP dissociation inhibitor 2*  / complex
 ENSMUSG00000015377 Q9D9V7 / Dennd6b / Protein DENND6B / Q8NEG7* / DENN domain containing 6B*  / reaction
 ENSMUSG00000078185 Chml / choroideremia-like / P26374* / CHM like, Rab escort protein 2*  / complex
 ENSMUSG00000019478 Rab4a / P56371 / Ras-related protein Rab-4A / P20338* / RAB4A, member RAS oncogene family*  / reaction / complex






 

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