Manteia

ENSDARG00000074246

Danio rerio

Features

Gene ID:	ENSDARG00000074246

Biological name :	rab14

Synonyms :	rab14 / RAB14, member RAS oncogene family

Possible biological names infered from orthology :	P61106 / Q91V41

Species:	Danio rerio

Chr. number:	5
Strand:	1
Band:
Gene start:	63390315
Gene end:	63399894

Corresponding Affymetrix probe sets:	Dr.7872.1.S1_at (Zebrafish Array) NM_201495_at (Zebrafish Genome Array with custom cdf files)

Cross references:	Ensembl peptide - ENSDARP00000106078 NCBI entrez gene - 373104 See in Manteia. RefSeq - NM_201495 RefSeq Peptide - NP_958903 swissprot - Q7ZVX4 ZFIN ID - ZDB-GENE-030826-20 Ensembl - ENSDARG00000074246

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
RAB14	ENSGALG00000001474	Gallus gallus
RAB14	ENSG00000119396	Homo sapiens
Rab14	ENSMUSG00000026878	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
rab14l / RAB14, member RAS oncogene family, like	ENSDARG00000035188	96
rab4b / RAB4B, member RAS oncogene family / Q91ZR1* / P61018* / RAB4B-EGLN2* / RAB4B-EGLN2 readthrough (NMD candidate)*	ENSDARG00000012177	59
rab4a / Q6PHI9 / RAB4a, member RAS oncogene family / P56371* / P20338* / Ras-related protein Rab-4A *	ENSDARG00000019144	58
rab2a / RAB2A, member RAS oncogene family / P53994* / P61019* / Ras-related protein Rab-2A *	ENSDARG00000020261	55
rab11al / RAB11a, member RAS oncogene family, like	ENSDARG00000014340	44
rab11a / RAB11a, member RAS oncogene family	ENSDARG00000041450	43
rab25a / RAB25, member RAS oncogene family a / RAB25* / Q9WTL2* / P57735* / RAB25, member RAS oncogene family*	ENSDARG00000058800	42
rab11ba / RAB11B, member RAS oncogene family, a / RAB11B* / P46638* / Q15907* / RAB11B, member RAS oncogene family*	ENSDARG00000041878	42
rab11bb / RAB11B, member RAS oncogene family, b / RAB11B* / P46638* / Q15907* / RAB11B, member RAS oncogene family*	ENSDARG00000090086	42
rab25b / RAB25, member RAS oncogene family b / RAB25* / P57735* / RAB25, member RAS oncogene family*	ENSDARG00000052954	41
rab18a / RAB18A, member RAS oncogene family / RAB18* / Q9NP72* / P35293* / RAB18, member RAS oncogene family*	ENSDARG00000055291	38
rab42a / RAB42, member RAS oncogene family a	ENSDARG00000034215	37
Q6DHC1 / rab18b / RAB18B, member RAS oncogene family / RAB18* / Q9NP72* / P35293* / RAB18, member RAS oncogene family*	ENSDARG00000098344	37
rab39ba / RAB39B, member RAS oncogene family a / RAB39B* / Q8BHC1* / Q96DA2* / RAB39B, member RAS oncogene family*	ENSDARG00000019312	37
rab39bb / RAB39B, member RAS oncogene family b / RAB39B* / Q8BHC1* / Q96DA2* / RAB39B, member RAS oncogene family*	ENSDARG00000036501	37
rab42b / RAB42, member RAS oncogene family	ENSDARG00000101170	36
si:dkey-34d22.2	ENSDARG00000100379	33
CU571310.1 / RAB42* / Q8N4Z0* / RAB42, member RAS oncogene family*	ENSDARG00000102580	30
si:dkey-34d22.5	ENSDARG00000104865	30
si:ch211-247i17.1	ENSDARG00000076727	19

Protein motifs (from Interpro)

Interpro ID	Name
IPR001806	Small GTPase superfamily
IPR005225	Small GTP-binding protein domain
IPR027417	P-loop containing nucleoside triphosphate hydrolase
IPR030702	Ras-related protein Rab14

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006895	Golgi to endosome transport	IEA
biological_process	GO:0030100	regulation of endocytosis	IBA
biological_process	GO:0032456	endocytic recycling	IEA
biological_process	GO:0042742	defense response to bacterium	IEA
biological_process	GO:0090382	phagosome maturation	IEA
cellular_component	GO:0005768	endosome	IBA
cellular_component	GO:0005802	trans-Golgi network	IEA
cellular_component	GO:0005829	cytosol	IEA
cellular_component	GO:0045335	phagocytic vesicle	IEA
cellular_component	GO:0055037	recycling endosome	IEA
molecular_function	GO:0003924	GTPase activity	IEA
molecular_function	GO:0005525	GTP binding	IEA

Pathways (from Reactome)

Pathway description

Neutrophil degranulation

RAB geranylgeranylation

RAB GEFs exchange GTP for GDP on RABs

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000056122	gdi1 / GDP dissociation inhibitor 1 / P31150* / P50396* / Rab GDP dissociation inhibitor alpha *	/ complex

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr