ENSMUSG00000047187


Mus musculus

Features
Gene ID: ENSMUSG00000047187
  
Biological name :Rab2a
  
Synonyms : P53994 / Rab2a / Ras-related protein Rab-2A
  
Possible biological names infered from orthology : P61019 / RAB2A, member RAS oncogene family
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: A1
Gene start: 8535644
Gene end: 8607778
  
Corresponding Affymetrix probe sets: 10503150 (MoGene1.0st)   10529873 (MoGene1.0st)   1418621_at (Mouse Genome 430 2.0 Array)   1418622_at (Mouse Genome 430 2.0 Array)   1418623_at (Mouse Genome 430 2.0 Array)   1419945_s_at (Mouse Genome 430 2.0 Array)   1419946_s_at (Mouse Genome 430 2.0 Array)   1436477_x_at (Mouse Genome 430 2.0 Array)   1449676_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000057664
NCBI entrez gene - 59021     See in Manteia.
MGI - MGI:1928750
RefSeq - XM_006538126
RefSeq - NM_021518
RefSeq Peptide - NP_067493
swissprot - P53994
swissprot - Q0PD65
Ensembl - ENSMUSG00000047187
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab2aENSDARG00000020261Danio rerio
 RAB2AENSGALG00000015450Gallus gallus
 RAB2AENSG00000104388Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rab2b / P59279 / RAB2B, member RAS oncogene family / Q8WUD1*ENSMUSG0000002215984
Rab14 / Q91V41 / RAB14, member RAS oncogene family / P61106*ENSMUSG0000002687856
Rab4a / P56371 / Ras-related protein Rab-4A / P20338* / RAB4A, member RAS oncogene family*ENSMUSG0000001947852
Rab4b / Q91ZR1 / RAB4B, member RAS oncogene family / P61018* / RAB4B-EGLN2* / RAB4B-EGLN2 readthrough (NMD candidate)*ENSMUSG0000005329151
P46638 / Rab11b / RAB11B, member RAS oncogene family / Q15907*ENSMUSG0000007745046
Rab39 / Q8BHD0 / RAB39, member RAS oncogene family / Q14964* / RAB39A* / RAB39A, member RAS oncogene family*ENSMUSG0000005506945
P62492 / Rab11a / RAB11A, member RAS oncogene family / P62491*ENSMUSG0000000477144
Q8BHC1 / Rab39b / RAB39B, member RAS oncogene family / Q96DA2*ENSMUSG0000003120242
Rab18 / P35293 / RAB18, member RAS oncogene family / Q9NP72*ENSMUSG0000007363942
Rab25 / Q9WTL2 / RAB25, member RAS oncogene family / P57735*ENSMUSG0000000860140
Rab42 / Q0PD08 / Ras-related protein Rab-42 / Q8N4Z0* / RAB42, member RAS oncogene family*ENSMUSG0000008968737


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport TAS
 biological_processGO:0007030 Golgi organization IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane IEA
 cellular_componentGO:0042470 melanosome IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity ISO
 molecular_functionGO:0005525 GTP binding ISO
 molecular_functionGO:0019003 GDP binding IEA


Pathways (from Reactome)
Pathway description
Golgi Cisternae Pericentriolar Stack Reorganization
RAB geranylgeranylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000026577 Blzf1 / Q8R2X8 / Golgin-45 / Q9H2G9* / basic leucine zipper nuclear factor 1*  / complex
 ENSMUSG00000014959 Q99JX3 / Gorasp2 / golgi reassembly stacking protein 2 / Q9H8Y8*  / complex






 

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