ENSG00000104388


Homo sapiens

Features
Gene ID: ENSG00000104388
  
Biological name :RAB2A
  
Synonyms : P61019 / RAB2A / RAB2A, member RAS oncogene family
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q12.1
Gene start: 60516857
Gene end: 60623627
  
Corresponding Affymetrix probe sets: 208730_x_at (Human Genome U133 Plus 2.0 Array)   208731_at (Human Genome U133 Plus 2.0 Array)   208732_at (Human Genome U133 Plus 2.0 Array)   208733_at (Human Genome U133 Plus 2.0 Array)   208734_x_at (Human Genome U133 Plus 2.0 Array)   221960_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000431589
Ensembl peptide - ENSP00000431846
Ensembl peptide - ENSP00000433875
Ensembl peptide - ENSP00000432855
Ensembl peptide - ENSP00000432735
Ensembl peptide - ENSP00000262646
Ensembl peptide - ENSP00000398054
NCBI entrez gene - 5862     See in Manteia.
OMIM - 179509
RefSeq - NM_002865
RefSeq - NM_001242644
RefSeq Peptide - NP_001229573
RefSeq Peptide - NP_002856
swissprot - H0YDL5
swissprot - H7C125
swissprot - E9PKL7
swissprot - P61019
swissprot - A0A1D5RMT4
swissprot - A0A024R7V6
swissprot - H0YD31
Ensembl - ENSG00000104388
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab2aENSDARG00000020261Danio rerio
 RAB2AENSGALG00000015450Gallus gallus
 Rab2aENSMUSG00000047187Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAB2B / Q8WUD1 / RAB2B, member RAS oncogene familyENSG0000012947284
RAB14 / P61106 / RAB14, member RAS oncogene familyENSG0000011939657
RAB4A / P20338 / RAB4A, member RAS oncogene familyENSG0000016811852
RAB4B-EGLN2 / RAB4B-EGLN2 readthrough (NMD candidate)ENSG0000017157051
RAB4B / P61018 / RAB4B, member RAS oncogene familyENSG0000016757851
Q15907 / RAB11B / RAB11B, member RAS oncogene familyENSG0000018523646
P62491 / RAB11A / RAB11A, member RAS oncogene familyENSG0000010376944
Q14964 / RAB39A / RAB39A, member RAS oncogene familyENSG0000017933144
RAB18 / Q9NP72 / RAB18, member RAS oncogene familyENSG0000009924643
RAB25 / P57735 / RAB25, member RAS oncogene familyENSG0000013269842
Q96DA2 / RAB39B / RAB39B, member RAS oncogene familyENSG0000015596142
RAB42 / Q8N4Z0 / RAB42, member RAS oncogene familyENSG0000018806016


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport TAS
 biological_processGO:0007030 Golgi organization IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005765 lysosomal membrane HDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane IEA
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0019003 GDP binding IDA


Pathways (from Reactome)
Pathway description
Golgi Cisternae Pericentriolar Stack Reorganization
RAB geranylgeranylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000115806 Q9H8Y8 / GORASP2 / golgi reassembly stacking protein 2  / complex
 ENSG00000117475 BLZF1 / Q9H2G9 / basic leucine zipper nuclear factor 1  / complex






 

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