ENSG00000168758


Homo sapiens

Features
Gene ID: ENSG00000168758
  
Biological name :SEMA4C
  
Synonyms : Q9C0C4 / SEMA4C / semaphorin 4C
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q11.2
Gene start: 96859716
Gene end: 96870757
  
Corresponding Affymetrix probe sets: 219039_at (Human Genome U133 Plus 2.0 Array)   46665_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000391094
Ensembl peptide - ENSP00000393498
Ensembl peptide - ENSP00000306844
NCBI entrez gene - 54910     See in Manteia.
OMIM - 604462
RefSeq - XM_017004394
RefSeq - XM_011511381
RefSeq - XM_011511382
RefSeq - XM_011511383
RefSeq - XM_017004393
RefSeq - NM_017789
RefSeq - XM_006712606
RefSeq - XM_011511378
RefSeq - XM_011511379
RefSeq - XM_011511380
RefSeq Peptide - NP_060259
swissprot - C9JV89
swissprot - C9J4M7
swissprot - Q9C0C4
Ensembl - ENSG00000168758
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sema4cENSDARG00000079611Danio rerio
 Q64151ENSMUSG00000026121Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NTN9 / SEMA4G / semaphorin 4GENSG0000009553940
SEMA4B / semaphorin 4BENSG0000018503336
Q92854 / SEMA4D / semaphorin 4DENSG0000018776434
Q9H3S1 / SEMA4A / semaphorin 4AENSG0000019618931
O95754 / SEMA4F / ssemaphorin 4FENSG0000013562230
Q13214 / SEMA3B / semaphorin 3BENSG0000001217128
Q14563 / SEMA3A / semaphorin 3AENSG0000007521328
O95025 / SEMA3D / semaphorin 3DENSG0000015399327
Q13275 / SEMA3F / semaphorin 3FENSG0000000161727
O15041 / SEMA3E / semaphorin 3EENSG0000017038126
Q9NS98 / SEMA3G / semaphorin 3GENSG0000001031926
Q99985 / SEMA3C / semaphorin 3CENSG0000007522324


Protein motifs (from Interpro)
Interpro ID Name
 IPR001627  Sema domain
 IPR002165  Plexin repeat
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016201  PSI domain
 IPR027231  Semaphorin
 IPR036179  Immunoglobulin-like domain superfamily
 IPR036352  Sema domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0021535 cell migration in hindbrain IEA
 biological_processGO:0021549 cerebellum development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade IDA
 biological_processGO:0042692 muscle cell differentiation IEA
 biological_processGO:0050919 negative chemotaxis IBA
 biological_processGO:0071526 semaphorin-plexin signaling pathway IEA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density ISS
 cellular_componentGO:0016020 membrane IBA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030672 synaptic vesicle membrane ISS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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