ENSG00000171056


Homo sapiens

Features
Gene ID: ENSG00000171056
  
Biological name :SOX7
  
Synonyms : Q9BT81 / SOX7 / SRY-box 7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: p23.1
Gene start: 10723768
Gene end: 10730512
  
Corresponding Affymetrix probe sets: 224013_s_at (Human Genome U133 Plus 2.0 Array)   228698_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000301921
NCBI entrez gene - 83595     See in Manteia.
OMIM - 612202
RefSeq - NM_031439
RefSeq Peptide - NP_113627
swissprot - Q9BT81
Ensembl - ENSG00000171056
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sox7ENSDARG00000030125Danio rerio
 ENSGALG00000041296Gallus gallus
 Sox7ENSMUSG00000063060Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC105001.2ENSG0000025872484
SOX17 / Q9H6I2 / SRY-box 17ENSG0000016473644
SOX18 / P35713 / SRY-box 18ENSG0000020388341
SOX8 / P57073 / SRY-box 8ENSG0000000551326
SOX9 / P48436 / SRY-box 9ENSG0000012539826
SOX10 / P56693 / SRY-box 10ENSG0000010014623
SOX11 / P35716 / SRY-box 11ENSG0000017688723
SOX4 / Q06945 / SRY-box 4ENSG0000012476623
SOX1 / O00570 / SRY-box 1ENSG0000018296822
SOX3 / P41225 / SRY-box 3ENSG0000013459522
SOX2 / P48431 / SRY-box 2ENSG0000018144920
SOX15 / O60248 / SRY-box 15ENSG0000012919419
SOX12 / O15370 / SRY-box 12ENSG0000017773218
SOX14 / O95416 / SRY-box 14ENSG0000016887517
SOX21 / Q9Y651 / SRY-box 21ENSG0000012528515
SRY / Q05066 / sex determining region YENSG0000018489514


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR021934  Sox, C-terminal
 IPR033392  Sox 7/17/18, central domain
 IPR036910  High mobility group box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001706 endoderm formation IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0060828 regulation of canonical Wnt signaling pathway IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA


Pathways (from Reactome)
Pathway description
Deactivation of the beta-catenin transactivating complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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