ENSG00000177732


Homo sapiens

Features
Gene ID: ENSG00000177732
  
Biological name :SOX12
  
Synonyms : O15370 / SOX12 / SRY-box 12
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: p13
Gene start: 325595
Gene end: 330224
  
Corresponding Affymetrix probe sets: 204432_at (Human Genome U133 Plus 2.0 Array)   228358_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000347646
NCBI entrez gene - 6666     See in Manteia.
OMIM - 601947
RefSeq - NM_006943
RefSeq Peptide - NP_008874
swissprot - O15370
Ensembl - ENSG00000177732
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sox12ENSDARG00000025847Danio rerio
 SOX12ENSGALG00000035951Gallus gallus
 Sox12ENSMUSG00000051817Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SOX4 / Q06945 / SRY-box 4ENSG0000012476649
SOX11 / P35716 / SRY-box 11ENSG0000017688742
SOX10 / P56693 / SRY-box 10ENSG0000010014624
SOX9 / P48436 / SRY-box 9ENSG0000012539824
SOX8 / P57073 / SRY-box 8ENSG0000000551323
SOX7 / Q9BT81 / SRY-box 7ENSG0000017105622
SOX15 / O60248 / SRY-box 15ENSG0000012919421
SOX18 / P35713 / SRY-box 18ENSG0000020388321
SOX17 / Q9H6I2 / SRY-box 17ENSG0000016473621
SOX3 / P41225 / SRY-box 3ENSG0000013459520
SOX2 / P48431 / SRY-box 2ENSG0000018144920
SOX21 / Q9Y651 / SRY-box 21ENSG0000012528520
SOX1 / O00570 / SRY-box 1ENSG0000018296820
SOX14 / O95416 / SRY-box 14ENSG0000016887518
SRY / Q05066 / sex determining region YENSG0000018489516
AC105001.2ENSG0000025872416


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR017386  Transcription factor SOX-11/4
 IPR031267  Transcription factor SOX-12
 IPR036910  High mobility group box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II NAS
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0021510 spinal cord development IEA
 biological_processGO:0045165 cell fate commitment IEP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0065004 protein-DNA complex assembly IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0032993 protein-DNA complex IEA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding NAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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