ENSG00000172828


Homo sapiens

Features
Gene ID: ENSG00000172828
  
Biological name :CES3
  
Synonyms : carboxylesterase 3 / CES3 / Q6UWW8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q22.1
Gene start: 66961237
Gene end: 66975148
  
Corresponding Affymetrix probe sets: 220335_x_at (Human Genome U133 Plus 2.0 Array)   234008_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000304782
Ensembl peptide - ENSP00000445559
Ensembl peptide - ENSP00000456203
Ensembl peptide - ENSP00000457547
Ensembl peptide - ENSP00000377602
NCBI entrez gene - 23491     See in Manteia.
OMIM - 605279
RefSeq - XM_011522976
RefSeq - NM_001185176
RefSeq - NM_001185177
RefSeq - NM_024922
RefSeq - XM_011522975
RefSeq Peptide - NP_001172106
RefSeq Peptide - NP_079198
RefSeq Peptide - NP_001172105
swissprot - Q6UWW8
swissprot - H3BRE5
swissprot - A0A0C4DFY7
swissprot - H3BUA3
Ensembl - ENSG00000172828
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ces2ENSDARG00000041569Danio rerio
 ces3ENSDARG00000041595Danio rerio
 si:ch211-93f2.1ENSDARG00000104818Danio rerio
 si:ch211-93f2.1ENSDARG00000101726Danio rerio
 Ces3aENSMUSG00000069922Mus musculus
 Ces3bENSMUSG00000062181Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CES2 / O00748 / carboxylesterase 2ENSG0000017283145
CES1 / P23141 / carboxylesterase 1ENSG0000019884843
CES5A / Q6NT32 / carboxylesterase 5AENSG0000015939842
ACHE / P22303 / acetylcholinesterase (Cartwright blood group)ENSG0000008708533
NLGN3 / Q9NZ94 / neuroligin 3ENSG0000019633833
NLGN1 / Q8N2Q7 / neuroligin 1ENSG0000016976032
NLGN2 / Q8NFZ4 / neuroligin 2ENSG0000016999232
CES4A / Q5XG92 / carboxylesterase 4AENSG0000017282432
NLGN4Y / Q8NFZ3 / neuroligin 4, Y-linkedENSG0000016524630
CEL / carboxyl ester lipaseENSG0000017083530
NLGN4X / Q8N0W4 / neuroligin 4, X-linkedENSG0000014693830
BCHE / P06276 / butyrylcholinesteraseENSG0000011420030


Protein motifs (from Interpro)
Interpro ID Name
 IPR002018  Carboxylesterase, type B
 IPR019826  Carboxylesterase type B, active site
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0034383 low-density lipoprotein particle clearance TAS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity TAS


Pathways (from Reactome)
Pathway description
Phase I - Functionalization of compounds
LDL clearance


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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