ENSG00000172831


Homo sapiens

Features
Gene ID: ENSG00000172831
  
Biological name :CES2
  
Synonyms : carboxylesterase 2 / CES2 / O00748
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q22.1
Gene start: 66934444
Gene end: 66945096
  
Corresponding Affymetrix probe sets: 209667_at (Human Genome U133 Plus 2.0 Array)   209668_x_at (Human Genome U133 Plus 2.0 Array)   213509_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000463641
Ensembl peptide - ENSP00000463166
Ensembl peptide - ENSP00000464620
Ensembl peptide - ENSP00000317842
Ensembl peptide - ENSP00000394452
Ensembl peptide - ENSP00000456167
Ensembl peptide - ENSP00000457721
NCBI entrez gene - 8824     See in Manteia.
OMIM - 605278
RefSeq - XM_017023818
RefSeq - NM_003869
RefSeq - NM_198061
RefSeq - XM_011523421
RefSeq Peptide - NP_932327
RefSeq Peptide - NP_003860
swissprot - A0A024R6X1
swissprot - H3BUN5
swissprot - J3QKN7
swissprot - J3QSC0
swissprot - J3QLP1
swissprot - O00748
Ensembl - ENSG00000172831
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ces2ENSDARG00000041569Danio rerio
 ces3ENSDARG00000041595Danio rerio
 si:ch211-93f2.1ENSDARG00000101726Danio rerio
 si:ch211-93f2.1ENSDARG00000104818Danio rerio
 CES2ENSGALG00000038923Gallus gallus
 Ces2aENSMUSG00000055730Mus musculus
 Ces2bENSMUSG00000050097Mus musculus
 Ces2cENSMUSG00000061825Mus musculus
 Ces2eENSMUSG00000031886Mus musculus
 Ces2fENSMUSG00000062826Mus musculus
 Ces2gENSMUSG00000031877Mus musculus
 Ces2hENSMUSG00000091813Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CES1 / P23141 / carboxylesterase 1ENSG0000019884842
CES3 / Q6UWW8 / carboxylesterase 3ENSG0000017282841
CES5A / Q6NT32 / carboxylesterase 5AENSG0000015939840
ACHE / P22303 / acetylcholinesterase (Cartwright blood group)ENSG0000008708531
CES4A / Q5XG92 / carboxylesterase 4AENSG0000017282430
NLGN3 / Q9NZ94 / neuroligin 3ENSG0000019633830
BCHE / P06276 / butyrylcholinesteraseENSG0000011420030
NLGN2 / Q8NFZ4 / neuroligin 2ENSG0000016999230
NLGN1 / Q8N2Q7 / neuroligin 1ENSG0000016976029
NLGN4X / Q8N0W4 / neuroligin 4, X-linkedENSG0000014693829
NLGN4Y / Q8NFZ3 / neuroligin 4, Y-linkedENSG0000016524629
CEL / carboxyl ester lipaseENSG0000017083527


Protein motifs (from Interpro)
Interpro ID Name
 IPR002018  Carboxylesterase, type B
 IPR019819  Carboxylesterase type B, conserved site
 IPR019826  Carboxylesterase type B, active site
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006693 prostaglandin metabolic process IDA
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0009056 catabolic process TAS
 cellular_componentGO:0005783 endoplasmic reticulum TAS
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0047374 methylumbelliferyl-acetate deacetylase activity IEA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity TAS


Pathways (from Reactome)
Pathway description
Phase I - Functionalization of compounds


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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