ENSG00000175161


Homo sapiens

Features
Gene ID: ENSG00000175161
  
Biological name :CADM2
  
Synonyms : CADM2 / cell adhesion molecule 2 / Q8N3J6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p12.1
Gene start: 84958981
Gene end: 86074429
  
Corresponding Affymetrix probe sets: 1552752_a_at (Human Genome U133 Plus 2.0 Array)   1552754_a_at (Human Genome U133 Plus 2.0 Array)   1555544_a_at (Human Genome U133 Plus 2.0 Array)   235118_at (Human Genome U133 Plus 2.0 Array)   240433_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000384193
Ensembl peptide - ENSP00000384575
Ensembl peptide - ENSP00000373200
NCBI entrez gene - 253559     See in Manteia.
OMIM - 609938
RefSeq - NM_001256504
RefSeq - NM_001256505
RefSeq - NM_153184
RefSeq - XM_017006063
RefSeq - NM_001167674
RefSeq - NM_001167675
RefSeq - NM_001256502
RefSeq - NM_001256503
RefSeq - XM_006713081
RefSeq - XM_006713082
RefSeq - XM_017006062
RefSeq Peptide - NP_001243432
RefSeq Peptide - NP_001243433
RefSeq Peptide - NP_001243434
RefSeq Peptide - NP_694854
RefSeq Peptide - NP_001161147
RefSeq Peptide - NP_001243431
RefSeq Peptide - NP_001161146
swissprot - Q8N3J6
swissprot - G3XHN4
Ensembl - ENSG00000175161
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cadm2aENSDARG00000009930Danio rerio
 cadm2bENSDARG00000062633Danio rerio
 CADM2ENSGALG00000043393Gallus gallus
 Cadm2ENSMUSG00000064115Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CADM3 / Q8N126 / cell adhesion molecule 3ENSG0000016270646
CADM1 / Q9BY67 / cell adhesion molecule 1ENSG0000018298544
CADM4 / Q8NFZ8 / cell adhesion molecule 4ENSG0000010576733
Q92692 / NECTIN2 / nectin cell adhesion molecule 2ENSG0000013020221
Q15223 / NECTIN1 / nectin cell adhesion molecule 1ENSG0000011040020
PVR / P15151 / poliovirus receptorENSG0000007300819
Q9NQS3 / NECTIN3 / nectin cell adhesion molecule 3ENSG0000017770719
Q96NY8 / NECTIN4 / nectin cell adhesion molecule 4ENSG0000014321718
CRTAM / O95727 / cytotoxic and regulatory T cell moleculeENSG0000010994317


Protein motifs (from Interpro)
Interpro ID Name
 IPR003585  Neurexin/syndecan/glycophorin C
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013162  CD80-like, immunoglobulin C2-set
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IBA
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IBA
 biological_processGO:0008037 cell recognition IBA
 biological_processGO:0034332 adherens junction organization TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0005913 cell-cell adherens junction IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0005102 signaling receptor binding IBA
 molecular_functionGO:0042803 protein homodimerization activity IBA
 molecular_functionGO:0050839 cell adhesion molecule binding IBA


Pathways (from Reactome)
Pathway description
Adherens junctions interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000175161 CADM2 / Q8N3J6 / cell adhesion molecule 2  / complex / reaction
 ENSG00000182985 CADM1 / Q9BY67 / cell adhesion molecule 1  / reaction / complex
 ENSG00000162706 CADM3 / Q8N126 / cell adhesion molecule 3  / reaction / complex






 

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