ENSG00000162706


Homo sapiens

Features
Gene ID: ENSG00000162706
  
Biological name :CADM3
  
Synonyms : CADM3 / cell adhesion molecule 3 / Q8N126
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q23.2
Gene start: 159171609
Gene end: 159203313
  
Corresponding Affymetrix probe sets: 211677_x_at (Human Genome U133 Plus 2.0 Array)   213948_x_at (Human Genome U133 Plus 2.0 Array)   216535_at (Human Genome U133 Plus 2.0 Array)   221921_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357106
Ensembl peptide - ENSP00000387802
Ensembl peptide - ENSP00000357107
NCBI entrez gene - 57863     See in Manteia.
OMIM - 609743
RefSeq - NM_001127173
RefSeq - NM_021189
RefSeq Peptide - NP_001120645
RefSeq Peptide - NP_067012
swissprot - A0A0C4DG09
swissprot - Q8N126
Ensembl - ENSG00000162706
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cadm3ENSDARG00000057013Danio rerio
 CADM3ENSGALG00000036925Gallus gallus
 Cadm3ENSMUSG00000005338Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CADM2 / Q8N3J6 / cell adhesion molecule 2ENSG0000017516147
CADM1 / Q9BY67 / cell adhesion molecule 1ENSG0000018298536
CADM4 / Q8NFZ8 / cell adhesion molecule 4ENSG0000010576732
Q92692 / NECTIN2 / nectin cell adhesion molecule 2ENSG0000013020222
Q15223 / NECTIN1 / nectin cell adhesion molecule 1ENSG0000011040021
PVR / P15151 / poliovirus receptorENSG0000007300820
Q96NY8 / NECTIN4 / nectin cell adhesion molecule 4ENSG0000014321720
Q9NQS3 / NECTIN3 / nectin cell adhesion molecule 3ENSG0000017770720
CRTAM / O95727 / cytotoxic and regulatory T cell moleculeENSG0000010994318


Protein motifs (from Interpro)
Interpro ID Name
 IPR003585  Neurexin/syndecan/glycophorin C
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013162  CD80-like, immunoglobulin C2-set
 IPR013783  Immunoglobulin-like fold
 IPR021157  Cytochrome c1, transmembrane anchor, C-terminal
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules ISS
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ISS
 biological_processGO:0008037 cell recognition IBA
 biological_processGO:0008104 protein localization IEA
 biological_processGO:0034332 adherens junction organization TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0005911 cell-cell junction ISS
 cellular_componentGO:0005913 cell-cell adherens junction IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005102 signaling receptor binding IBA
 molecular_functionGO:0042803 protein homodimerization activity ISS
 molecular_functionGO:0050839 cell adhesion molecule binding IBA


Pathways (from Reactome)
Pathway description
Adherens junctions interactions
Nectin/Necl trans heterodimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000110400 Q15223 / NECTIN1 / nectin cell adhesion molecule 1  / complex / reaction
 ENSG00000177707 Q9NQS3 / NECTIN3 / nectin cell adhesion molecule 3  / complex / reaction
 ENSG00000182985 CADM1 / Q9BY67 / cell adhesion molecule 1  / complex / reaction
 ENSG00000162706 CADM3 / Q8N126 / cell adhesion molecule 3  / reaction / complex
 ENSG00000175161 CADM2 / Q8N3J6 / cell adhesion molecule 2  / reaction / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr