ENSMUSG00000005338


Mus musculus

Features
Gene ID: ENSMUSG00000005338
  
Biological name :Cadm3
  
Synonyms : Cadm3 / Cell adhesion molecule 3 / Q99N28
  
Possible biological names infered from orthology : Q8N126
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: H3
Gene start: 173333258
Gene end: 173367695
  
Corresponding Affymetrix probe sets: 10360349 (MoGene1.0st)   1418921_at (Mouse Genome 430 2.0 Array)   1418922_at (Mouse Genome 430 2.0 Array)   1449272_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000005470
Ensembl peptide - ENSMUSP00000106851
NCBI entrez gene - 94332     See in Manteia.
MGI - MGI:2137858
RefSeq - NM_053199
RefSeq - XM_006497060
RefSeq Peptide - NP_444429
swissprot - K4DI58
swissprot - Q99N28
Ensembl - ENSMUSG00000005338
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cadm3ENSDARG00000057013Danio rerio
 CADM3ENSGALG00000036925Gallus gallus
 CADM3ENSG00000162706Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cadm2 / Q8BLQ9 / Cell adhesion molecule 2 / Q8N3J6*ENSMUSG0000006411549
Cadm1 / Q8R5M8 / Cell adhesion molecule 1 / Q9BY67*ENSMUSG0000003207639
Cadm4 / Q8R464 / Cell adhesion molecule 4 / Q8NFZ8*ENSMUSG0000005479335
P32507 / Nectin2 / Q92692* / nectin cell adhesion molecule 2*ENSMUSG0000006230023
Q8R007 / Nectin4 / Q96NY8* / nectin cell adhesion molecule 4*ENSMUSG0000000641123
Q9JKF6 / Nectin1 / Q15223* / nectin cell adhesion molecule 1*ENSMUSG0000003201222
Q9JLB9 / Nectin3 / Q9NQS3* / nectin cell adhesion molecule 3*ENSMUSG0000002265621
Crtam / cytotoxic and regulatory T cell molecule / O95727*ENSMUSG0000003202119
Pvr / poliovirus receptor / P15151*ENSMUSG0000004051119


Protein motifs (from Interpro)
Interpro ID Name
 IPR003585  Neurexin/syndecan/glycophorin C
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013162  CD80-like, immunoglobulin C2-set
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IDA
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IDA
 biological_processGO:0008037 cell recognition IBA
 biological_processGO:0008104 protein localization IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0005913 cell-cell adherens junction IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005102 signaling receptor binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0050839 cell adhesion molecule binding IBA


Pathways (from Reactome)
Pathway description
Adherens junctions interactions
Nectin/Necl trans heterodimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000920 abnormal myelination "atypical or altered myelination in axon sheaths" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Wnt7btm2Amc/Wnt7btm2.1Amc,Tg(Hoxb7-cre)13Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000005338 Cadm3 / Q99N28 / Cell adhesion molecule 3 / Q8N126*  / reaction / complex
 ENSMUSG00000064115 Cadm2 / Q8BLQ9 / Cell adhesion molecule 2 / Q8N3J6*  / complex / reaction
 ENSMUSG00000022656 Q9JLB9 / Nectin3 / Q9NQS3* / nectin cell adhesion molecule 3*  / reaction / complex
 ENSMUSG00000032076 Cadm1 / Q8R5M8 / Cell adhesion molecule 1 / Q9BY67*  / reaction / complex
 ENSMUSG00000032012 Q9JKF6 / Nectin1 / Q15223* / nectin cell adhesion molecule 1*  / reaction / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr