ENSMUSG00000006411


Mus musculus

Features
Gene ID: ENSMUSG00000006411
  
Biological name :Nectin4
  
Synonyms : Nectin4 / Q8R007
  
Possible biological names infered from orthology : nectin cell adhesion molecule 4 / Q96NY8
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: H3
Gene start: 171370099
Gene end: 171388598
  
Corresponding Affymetrix probe sets: 10351588 (MoGene1.0st)   1428701_at (Mouse Genome 430 2.0 Array)   1451690_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000006578
Ensembl peptide - ENSMUSP00000091883
Ensembl peptide - ENSMUSP00000106917
NCBI entrez gene - 71740     See in Manteia.
MGI - MGI:1918990
RefSeq - NM_001122680
RefSeq - NM_027893
RefSeq Peptide - NP_001116152
RefSeq Peptide - NP_082169
swissprot - Q8R007
Ensembl - ENSMUSG00000006411
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nectin4ENSDARG00000103148Danio rerio
 si:ch211-119e14.9ENSDARG00000077419Danio rerio
 Q96NY8ENSG00000143217Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9JLB9 / Nectin3 / Q9NQS3* / nectin cell adhesion molecule 3*ENSMUSG0000002265627
P32507 / Nectin2 / Q92692* / nectin cell adhesion molecule 2*ENSMUSG0000006230023
Q9JKF6 / Nectin1 / Q15223* / nectin cell adhesion molecule 1*ENSMUSG0000003201223
Pvr / poliovirus receptor / P15151*ENSMUSG0000004051120
Cadm3 / Q99N28 / Cell adhesion molecule 3 / Q8N126*ENSMUSG0000000533818
Cadm1 / Q8R5M8 / Cell adhesion molecule 1 / Q9BY67*ENSMUSG0000003207616
Cadm4 / Q8R464 / Cell adhesion molecule 4 / Q8NFZ8*ENSMUSG0000005479316
Cadm2 / Q8BLQ9 / Cell adhesion molecule 2 / Q8N3J6*ENSMUSG0000006411516
Crtam / cytotoxic and regulatory T cell molecule / O95727*ENSMUSG0000003202112


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013162  CD80-like, immunoglobulin C2-set
 IPR013783  Immunoglobulin-like fold
 IPR033320  Nectin-4
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IBA
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IBA
 biological_processGO:0008037 cell recognition IBA
 biological_processGO:0046718 viral entry into host cell IEA
 biological_processGO:0098609 cell-cell adhesion ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0005912 adherens junction ISO
 cellular_componentGO:0005913 cell-cell adherens junction IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005102 signaling receptor binding IBA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity IBA
 molecular_functionGO:0050839 cell adhesion molecule binding IBA


Pathways (from Reactome)
Pathway description
Adherens junctions interactions
Nectin/Necl trans heterodimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000022656 Q9JLB9 / Nectin3 / Q9NQS3* / nectin cell adhesion molecule 3*  / reaction / complex
 ENSMUSG00000006411 Q8R007 / Nectin4 / Q96NY8* / nectin cell adhesion molecule 4*  / reaction / complex
 ENSMUSG00000062300 P32507 / Nectin2 / Q92692* / nectin cell adhesion molecule 2*  / complex / reaction
 ENSMUSG00000032012 Q9JKF6 / Nectin1 / Q15223* / nectin cell adhesion molecule 1*  / complex / reaction
 ENSMUSG00000068036 Afdn / Q9QZQ1 / Afadin / P55196* / afadin, adherens junction formation factor*  / complex / reaction






 

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