ENSG00000182985


Homo sapiens

Features
Gene ID: ENSG00000182985
  
Biological name :CADM1
  
Synonyms : CADM1 / cell adhesion molecule 1 / Q9BY67
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q23.3
Gene start: 115169218
Gene end: 115504957
  
Corresponding Affymetrix probe sets: 209030_s_at (Human Genome U133 Plus 2.0 Array)   209031_at (Human Genome U133 Plus 2.0 Array)   209032_s_at (Human Genome U133 Plus 2.0 Array)   232767_at (Human Genome U133 Plus 2.0 Array)   244345_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000442387
Ensembl peptide - ENSP00000442227
Ensembl peptide - ENSP00000445375
Ensembl peptide - ENSP00000484516
Ensembl peptide - ENSP00000483648
Ensembl peptide - ENSP00000329797
Ensembl peptide - ENSP00000395359
Ensembl peptide - ENSP00000439176
Ensembl peptide - ENSP00000439696
Ensembl peptide - ENSP00000439817
Ensembl peptide - ENSP00000439847
Ensembl peptide - ENSP00000440322
Ensembl peptide - ENSP00000442001
NCBI entrez gene - 23705     See in Manteia.
OMIM - 605686
RefSeq - XM_017017461
RefSeq - NM_001098517
RefSeq - NM_001301043
RefSeq - NM_001301044
RefSeq - NM_001301045
RefSeq - NM_014333
RefSeq - XM_005271494
RefSeq - XM_017017457
RefSeq - XM_017017458
RefSeq - XM_017017459
RefSeq - XM_017017460
RefSeq Peptide - NP_001287972
RefSeq Peptide - NP_001287973
RefSeq Peptide - NP_001287974
RefSeq Peptide - NP_055148
RefSeq Peptide - NP_001091987
swissprot - F5H0H5
swissprot - F5H125
swissprot - F5H372
swissprot - F5H8J9
swissprot - H0YG94
swissprot - X5D7A8
swissprot - X5D8W0
swissprot - X5DQS5
swissprot - X5DQR8
swissprot - A0A087X0T8
swissprot - Q9BY67
swissprot - A0A0A0MTJ8
swissprot - A0A087X1W8
Ensembl - ENSG00000182985
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cadm1aENSDARG00000031075Danio rerio
 cadm1bENSDARG00000042677Danio rerio
 CADM1ENSGALG00000014582Gallus gallus
 Cadm1ENSMUSG00000032076Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CADM2 / Q8N3J6 / cell adhesion molecule 2ENSG0000017516141
CADM3 / Q8N126 / cell adhesion molecule 3ENSG0000016270633
CADM4 / Q8NFZ8 / cell adhesion molecule 4ENSG0000010576732
Q15223 / NECTIN1 / nectin cell adhesion molecule 1ENSG0000011040019
Q9NQS3 / NECTIN3 / nectin cell adhesion molecule 3ENSG0000017770718
Q92692 / NECTIN2 / nectin cell adhesion molecule 2ENSG0000013020218
Q96NY8 / NECTIN4 / nectin cell adhesion molecule 4ENSG0000014321718
CRTAM / O95727 / cytotoxic and regulatory T cell moleculeENSG0000010994317
PVR / P15151 / poliovirus receptorENSG0000007300816


Protein motifs (from Interpro)
Interpro ID Name
 IPR003585  Neurexin/syndecan/glycophorin C
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013162  CD80-like, immunoglobulin C2-set
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IBA
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ISS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0008037 cell recognition ISS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0034332 adherens junction organization TAS
 biological_processGO:0042271 susceptibility to natural killer cell mediated cytotoxicity ISS
 biological_processGO:0045954 positive regulation of natural killer cell mediated cytotoxicity ISS
 biological_processGO:0050715 positive regulation of cytokine secretion IDA
 biological_processGO:0051606 detection of stimulus ISS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0005911 cell-cell junction ISS
 cellular_componentGO:0005913 cell-cell adherens junction IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane ISS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005102 signaling receptor binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030165 PDZ domain binding ISS
 molecular_functionGO:0042803 protein homodimerization activity IBA
 molecular_functionGO:0050839 cell adhesion molecule binding IBA


Pathways (from Reactome)
Pathway description
Adherens junctions interactions
Nectin/Necl trans heterodimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000177707 Q9NQS3 / NECTIN3 / nectin cell adhesion molecule 3  / complex / reaction
 ENSG00000162706 CADM3 / Q8N126 / cell adhesion molecule 3  / reaction / complex
 ENSG00000182985 CADM1 / Q9BY67 / cell adhesion molecule 1  / complex / reaction
 ENSG00000175161 CADM2 / Q8N3J6 / cell adhesion molecule 2  / complex / reaction






 

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