ENSG00000180535


Homo sapiens

Features
Gene ID: ENSG00000180535
  
Biological name :BHLHA15
  
Synonyms : basic helix-loop-helix family member a15 / BHLHA15 / Q7RTS1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q21.3
Gene start: 98211427
Gene end: 98212979
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000476312
Ensembl peptide - ENSP00000326391
NCBI entrez gene - 168620     See in Manteia.
OMIM - 608606
RefSeq - NM_177455
RefSeq Peptide - NP_803238
swissprot - Q7RTS1
Ensembl - ENSG00000180535
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bhlha15ENSDARG00000045166Danio rerio
 ENSGALG00000031306Gallus gallus
 Q9QYC3ENSMUSG00000052271Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q15784 / NEUROD2 / neuronal differentiation 2ENSG0000017153228
Q9HD90 / NEUROD4 / neuronal differentiation 4ENSG0000012330725
ATOH1 / Q92858 / atonal bHLH transcription factor 1ENSG0000017223825
Q9H2A3 / NEUROG2 / neurogenin 2ENSG0000017840325
Q96NK8 / NEUROD6 / neuronal differentiation 6ENSG0000016460025
Q92886 / NEUROG1 / neurogenin 1ENSG0000018196524
Q13562 / NEUROD1 / neuronal differentiation 1ENSG0000016299224
Q9Y4Z2 / NEUROG3 / neurogenin 3ENSG0000012285923
ATOH8 / Q96SQ7 / atonal bHLH transcription factor 8ENSG0000016887423
ATOH7 / Q8N100 / atonal bHLH transcription factor 7ENSG0000017977420


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006851 mitochondrial calcium ion transmembrane transport IEA
 biological_processGO:0007030 Golgi organization IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007267 cell-cell signaling IEA
 biological_processGO:0010832 negative regulation of myotube differentiation ISS
 biological_processGO:0019722 calcium-mediated signaling IEA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response ISS
 biological_processGO:0042149 cellular response to glucose starvation ISS
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048312 intracellular distribution of mitochondria IEA
 biological_processGO:0048469 cell maturation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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