ENSG00000179774


Homo sapiens

Features
Gene ID: ENSG00000179774
  
Biological name :ATOH7
  
Synonyms : ATOH7 / atonal bHLH transcription factor 7 / Q8N100
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q21.3
Gene start: 68230624
Gene end: 68232103
  
Corresponding Affymetrix probe sets: 1552878_at (Human Genome U133 Plus 2.0 Array)   1552879_a_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362777
NCBI entrez gene - 220202     See in Manteia.
OMIM - 609875
RefSeq - NM_145178
RefSeq Peptide - NP_660161
swissprot - F1T0H4
swissprot - Q8N100
Ensembl - ENSG00000179774
  
Related genetic diseases (OMIM): 221900 - Persistent hyperplastic primary vitreous, autosomal recessive, 221900

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atoh7ENSDARG00000069552Danio rerio
 ATOH7ENSGALG00000003931Gallus gallus
 7 ENSMUSG00000036816Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ATOH1 / Q92858 / atonal bHLH transcription factor 1ENSG0000017223836
Q92886 / NEUROG1 / neurogenin 1ENSG0000018196530
Q15784 / NEUROD2 / neuronal differentiation 2ENSG0000017153229
Q96NK8 / NEUROD6 / neuronal differentiation 6ENSG0000016460028
Q9H2A3 / NEUROG2 / neurogenin 2ENSG0000017840328
Q9HD90 / NEUROD4 / neuronal differentiation 4ENSG0000012330728
Q9Y4Z2 / NEUROG3 / neurogenin 3ENSG0000012285928
Q13562 / NEUROD1 / neuronal differentiation 1ENSG0000016299227
ATOH8 / Q96SQ7 / atonal bHLH transcription factor 8ENSG0000016887424
Q7RTS1 / BHLHA15 / basic helix-loop-helix family member a15ENSG0000018053524


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR032663  Protein atonal homologue 7
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003407 neural retina development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007623 circadian rhythm IEA
 biological_processGO:0009649 entrainment of circadian clock IEA
 biological_processGO:0021554 optic nerve development IMP
 biological_processGO:0030154 cell differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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