ENSDARG00000069552


Danio rerio

Features
Gene ID: ENSDARG00000069552
  
Biological name :atoh7
  
Synonyms : atoh7 / atonal bHLH transcription factor 7 / Q8AW52
  
Possible biological names infered from orthology : 7 / Q8N100 / Q9Z2E5
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 25449681
Gene end: 25450725
  
Corresponding Affymetrix probe sets: Dr.10453.1.S1_at (Zebrafish Array)   NM_131632_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000092102
NCBI entrez gene - 58216     See in Manteia.
RefSeq - NM_131632
RefSeq Peptide - NP_571707
swissprot - Q8AW52
ZFIN ID - ZDB-GENE-000926-1
Ensembl - ENSDARG00000069552
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ATOH7ENSGALG00000003931Gallus gallus
 ATOH7ENSG00000179774Homo sapiens
 7 ENSMUSG00000036816Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
atoh1a / atonal bHLH transcription factor 1a / 1 * / ATOH1* / P48985* / Q92858* / atonal bHLH transcription factor 1*ENSDARG0000005529437
neurod2 / neurogenic differentiation 2 / Q15784* / Q62414* / neuronal differentiation 2*ENSDARG0000001685435
atoh1c / atonal bHLH transcription factor 1cENSDARG0000003960233
O42202 / neurod1 / neuronal differentiation 1 / Q13562* / Q60867* / Neurogenic differentiation factor 1 *ENSDARG0000001956633
Q6NYU3 / neurod6a / neuronal differentiation 6a / Q96NK8* / P48986* / NEUROD6* / neuronal differentiation 6* / neurogenic differentiation 6*ENSDARG0000004000831
neurod4 / neuronal differentiation 4 / O09105* / Q9HD90* / neurogenic differentiation 4*ENSDARG0000000346931
Q9W6C7 / neurod6b / neuronal differentiation 6b / Q96NK8* / NEUROD6* / neuronal differentiation 6*ENSDARG0000002079429
O42606 / neurog1 / neurogenin 1 / Q9H2A3* / NEUROG2* / neurogenin 2*ENSDARG0000005613028
neurog3 / neurogenin 3 / P70661* / Q9Y4Z2*ENSDARG0000001695125
bhlha15 / basic helix-loop-helix family, member a15 / Q7RTS1* / Q9QYC3* / Class A basic helix-loop-helix protein 15 *ENSDARG0000004516625
atoh8 / D2CLZ9 / atonal bHLH transcription factor 8 / 8 * / Q96SQ7* / Q99NA2*ENSDARG0000003755522
BX957231.1ENSDARG000001147487


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR032663  Protein atonal homologue 7


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001654 eye development IMP
 biological_processGO:0003407 neural retina development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0010842 retina layer formation IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0036269 swimming behavior IMP
 biological_processGO:0043010 camera-type eye development IMP
 biological_processGO:0043473 pigmentation IMP
 biological_processGO:0045165 cell fate commitment IMP
 biological_processGO:0050769 positive regulation of neurogenesis IMP
 biological_processGO:0051726 regulation of cell cycle IMP
 biological_processGO:0060041 retina development in camera-type eye IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye quality , abnormal
eye morphology , abnormal
eye decreased size , abnormal
Show

 ZFA:0000143 retinal photoreceptor layer retinal photoreceptor layer photoreceptor cell absent , abnormal
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 ZFA:0000282 sensory system sensory system quality , abnormal
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 ZFA:0000396 nervous system nervous system quality , abnormal
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 ZFA:0001094 whole organism whole organism increased amount , abnormal
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 ZFA:0001329 retinal inner plexiform layer retinal inner plexiform layer increased thickness , abnormal
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 ZFA:0009090 pigment cell pigment cell quality , abnormal
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 ZFA:0009091 melanocyte melanocyte area , abnormal
melanocyte melanosome spatial pattern , abnormal
melanocyte melanosome dispersed , abnormal
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 ZFA:0009310 retinal ganglion cell retinal ganglion cell decreased amount , abnormal
retinal ganglion cell absent , abnormal
Show

 ZFA:0009318 retinal bipolar neuron retinal bipolar neuron increased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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