ENSDARG00000055294


Danio rerio

Features
Gene ID: ENSDARG00000055294
  
Biological name :atoh1a
  
Synonyms : atoh1a / atonal bHLH transcription factor 1a
  
Possible biological names infered from orthology : 1 / ATOH1 / atonal bHLH transcription factor 1 / P48985 / Q92858
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 29593986
Gene end: 29595615
  
Corresponding Affymetrix probe sets: Dr.566.1.S1_at (Zebrafish Array)   NM_131091_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000105581
NCBI entrez gene - 30303     See in Manteia.
RefSeq - NM_131091
RefSeq Peptide - NP_571166
swissprot - B0R059
ZFIN ID - ZDB-GENE-990415-17
Ensembl - ENSDARG00000055294
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ATOH1ENSG00000172238Homo sapiens
 1 ENSMUSG00000073043Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
atoh1c / atonal bHLH transcription factor 1cENSDARG0000003960219
Q9W6C7 / neurod6b / neuronal differentiation 6b / Q96NK8* / NEUROD6* / neuronal differentiation 6*ENSDARG0000002079417
neurod4 / neuronal differentiation 4 / O09105* / Q9HD90* / neurogenic differentiation 4*ENSDARG0000000346917
O42606 / neurog1 / neurogenin 1 / Q9H2A3* / NEUROG2* / neurogenin 2*ENSDARG0000005613017
atoh7 / Q8AW52 / atonal bHLH transcription factor 7 / 7 * / Q8N100* / Q9Z2E5*ENSDARG0000006955217
O42202 / neurod1 / neuronal differentiation 1 / Q13562* / Q60867* / Neurogenic differentiation factor 1 *ENSDARG0000001956616
neurog3 / neurogenin 3 / P70661* / Q9Y4Z2*ENSDARG0000001695116
Q6NYU3 / neurod6a / neuronal differentiation 6a / Q96NK8* / P48986* / NEUROD6* / neuronal differentiation 6* / neurogenic differentiation 6*ENSDARG0000004000815
neurod2 / neurogenic differentiation 2 / Q15784* / Q62414* / neuronal differentiation 2*ENSDARG0000001685415
bhlha15 / basic helix-loop-helix family, member a15 / Q7RTS1* / Q9QYC3* / Class A basic helix-loop-helix protein 15 *ENSDARG0000004516613
atoh8 / D2CLZ9 / atonal bHLH transcription factor 8 / 8 * / Q96SQ7* / Q99NA2*ENSDARG0000003755512
BX957231.1ENSDARG000001147483


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0035675 neuromast hair cell development IMP
 biological_processGO:0042491 inner ear auditory receptor cell differentiation IEA
 biological_processGO:0042668 auditory receptor cell fate determination IMP
 biological_processGO:0048839 inner ear development IMP
 biological_processGO:0048884 neuromast development IMP
 biological_processGO:0048919 posterior lateral line neuromast development IMP
 biological_processGO:0048923 posterior lateral line neuromast hair cell differentiation IMP
 biological_processGO:0060119 inner ear receptor cell development IMP
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000243 neuromast neuromast absent , abnormal
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 ZFA:0000588 statoacoustic (VIII) ganglion statoacoustic (VIII) ganglion anatomical region decreased size , abnormal
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 ZFA:0000940 posterior lateral line neuromast posterior lateral line neuromast decreased amount , abnormal
posterior lateral line neuromast neuromast hair cell absent , abnormal
Show

 ZFA:0009366 hair cell hair cell absent , abnormal
hair cell decreased amount , abnormal
Show

 ZFA:0009367 neuromast hair cell neuromast hair cell absent , abnormal
neuromast hair cell kinocilium absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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