ENSG00000171532


Homo sapiens

Features
Gene ID: ENSG00000171532
  
Biological name :NEUROD2
  
Synonyms : NEUROD2 / neuronal differentiation 2 / Q15784
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q12
Gene start: 39603536
Gene end: 39609777
  
Corresponding Affymetrix probe sets: 1552953_a_at (Human Genome U133 Plus 2.0 Array)   210271_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000306754
NCBI entrez gene - 4761     See in Manteia.
OMIM - 601725
RefSeq - NM_006160
RefSeq Peptide - NP_006151
swissprot - Q15784
Ensembl - ENSG00000171532
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 neurod2ENSDARG00000016854Danio rerio
 NEUROD2ENSGALG00000039633Gallus gallus
 Q62414ENSMUSG00000038255Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q13562 / NEUROD1 / neuronal differentiation 1ENSG0000016299249
Q96NK8 / NEUROD6 / neuronal differentiation 6ENSG0000016460044
Q9HD90 / NEUROD4 / neuronal differentiation 4ENSG0000012330739
Q92886 / NEUROG1 / neurogenin 1ENSG0000018196518
ATOH8 / Q96SQ7 / atonal bHLH transcription factor 8ENSG0000016887415
Q9H2A3 / NEUROG2 / neurogenin 2ENSG0000017840315
Q9Y4Z2 / NEUROG3 / neurogenin 3ENSG0000012285914
Q7RTS1 / BHLHA15 / basic helix-loop-helix family member a15ENSG0000018053514
ATOH1 / Q92858 / atonal bHLH transcription factor 1ENSG0000017223814
ATOH7 / Q8N100 / atonal bHLH transcription factor 7ENSG0000017977412


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR016637  Neurogenic differentiation factor NeuroD
 IPR022575  Neurogenic differentiation factor, domain of unknown function
 IPR032649  Neurogenic differentiation factor 2
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001662 behavioral fear response IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development TAS
 biological_processGO:0008306 associative learning IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0021695 cerebellar cortex development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031915 positive regulation of synaptic plasticity IEA
 biological_processGO:0045664 regulation of neuron differentiation IEA
 biological_processGO:0045666 positive regulation of neuron differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048666 neuron development IEA
 biological_processGO:0050850 positive regulation of calcium-mediated signaling IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0071257 cellular response to electrical stimulus IEA
 biological_processGO:0071277 cellular response to calcium ion IEA
 biological_processGO:0090128 regulation of synapse maturation IEA
 biological_processGO:0090129 positive regulation of synapse maturation IEA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 biological_processGO:2000297 negative regulation of synapse maturation IEA
 cellular_componentGO:0005634 nucleus ISS
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA
 molecular_functionGO:0070888 E-box binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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