ENSG00000178403


Homo sapiens

Features
Gene ID: ENSG00000178403
  
Biological name :NEUROG2
  
Synonyms : NEUROG2 / neurogenin 2 / Q9H2A3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q25
Gene start: 112513516
Gene end: 112516172
  
Corresponding Affymetrix probe sets: 215632_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000317333
NCBI entrez gene - 63973     See in Manteia.
OMIM - 606624
RefSeq - NM_024019
RefSeq Peptide - NP_076924
swissprot - Q9H2A3
Ensembl - ENSG00000178403
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 O42606ENSDARG00000056130Danio rerio
 Neurog2ENSMUSG00000027967Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q92886 / NEUROG1 / neurogenin 1ENSG0000018196534
Q9Y4Z2 / NEUROG3 / neurogenin 3ENSG0000012285927
ATOH1 / Q92858 / atonal bHLH transcription factor 1ENSG0000017223825
Q96NK8 / NEUROD6 / neuronal differentiation 6ENSG0000016460024
Q9HD90 / NEUROD4 / neuronal differentiation 4ENSG0000012330723
Q15784 / NEUROD2 / neuronal differentiation 2ENSG0000017153221
Q13562 / NEUROD1 / neuronal differentiation 1ENSG0000016299221
ATOH8 / Q96SQ7 / atonal bHLH transcription factor 8ENSG0000016887419
Q7RTS1 / BHLHA15 / basic helix-loop-helix family member a15ENSG0000018053518
ATOH7 / Q8N100 / atonal bHLH transcription factor 7ENSG0000017977415


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR032655  Neurogenin-2
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity ISS
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA
 molecular_functionGO:0070888 E-box binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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